en Contributors are those that engage in discussions in the context of SIO (in alphabetical order): sivaram arabandi christopher baker joachim baran jerven bolleman matthew brush alison callahan leonid chepelev kevin cohen melanie courtot geraint duck laura furlong elisa kendall tatsuya kushida luke mccarthy jim mccusker jose miguel cruz-toledo chris mungall robert hoehndorf simon jupp jin-dong kim dana klassen thomas luetteke james malone chris mungall david osumi-sutherland tazro ohta nuria queralt stephen reed alexandre riazanov matthias samwald robert stevens mark wilkinson karin verspoor natalia villanueva-rosales Michel Dumontier http://orcid.org/0000-0003-4727-9435 The semanticscience integrated ontology (SIO) provides a simple, integrated ontology (types, relations) for objects, processes and their attributes. This project provides foundational support for the Bio2RDF (http://bio2rdf.org) and SADI (http://sadiframework.org) projects. website: http://semanticscience.org email: sio-ontology@googlegroups.com mailing list: http://groups.google.com/group/sio-ontology 2010-03-29 free to use,share,modify. modify with attribution [http://creativecommons.org/licenses/by/4.0/]. Semanticscience Integrated Ontology (SIO) http://www.jbiomedsem.com/content/5/1/14 sio http://semanticscience.org/resource/ general class inclusion axioms: 'is part of' some 'physical entity' subClassOf 'is located in' some 'physical entity' role chains: 'has capability' o 'is realized in' -> 'is participant in' http://sio.semanticscience.org 1.59 sio-subset-camelcase-label.owl A is related to B iff there is some relation between A and B. 'is related to' is the top level relation in SIO core relations+ is related to has attribute is a relation that associates a entity with an attribute where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type. core has attribute is attribute of is a relation that associates an attribute with an entity where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type. is attribute of denotes is a relation between an entity and what it is a sign or indication of, or what specifically means. denotes the symbol '%' denotes a proportion in relation to a whole. has part is a transitive, reflexive and antisymmetric relation between a whole and itself or a whole and its part. has part a collection of cars has as a car as a part;a car has an engine as a part; a car has a piston as a part; is time boundary of has proper part is an antisymmetric, irreflexive (normally transitive) relation between a whole and a distinct part. has proper part a car has an engine as a proper part; a car has a piston as a proper part; has boundary is a mereological relation between a whole and boundary located at its periphery. has boundary the surface of an apple is a 2D boundary of the apple. has member is a mereological relation between a collection and an item. core has member a collection of cars has as a car as a member is denoted by A is located in B iff the spatialtemporial region occupied by A is part of the spatialtemporal region occupied by B. [T][R] OBO_REL:located_in core is located in A parasite in the interior of a person's intestine is located in their intestinal lumen. is participant in is a relation that describes the participation of the subject in the (processual) object. is participant in a car is a participant in a car race; glucose is a participant in glycolysis is agent in is a relation between an entity and a process, where the entity is present throughout the process, no permanent material change occurs, and is a causal participant in the process. sadi is agent in hexokinase is an agent in the conversion of glucose to glucose-6-phosphate is provider of is a relation between a source and the entity it makes available. is provider of is provided by is a relation between an entity and the entity that provides it. dc:source has provider is part of is a transitive, reflexive and anti-symmetric mereological relation between a whole and itself or a part and its whole. OBO_REL:part_of core is part of is proper part of is an asymmetric, irreflexive (normally transitive) relation between a part and its distinct whole. OBO_REL:proper_part_of core is proper part of is member of is a mereological relation between a item and a collection. is member of is boundary of is a mereological relation between a boundary located at the periphery of a whole. is boundary of A is contained in B iff the spatial region occupied by A is part of the spatial region occupied by B and A is not part of B. [T] OBO_REL:contained_in core is contained in has participant is a relation that describes the participation of the object in the (processual) subject. OBO_REL:has_participant core has participant has agent is a relation between a process and an entity, where the entity is present throughout the process and is a causal participant in the process. OBO_REL:has_agent core sadi has agent A is location of B iff the spatialtemporal region occupied by A has the spatialtemporal region occupied by B as a part. [T][R] nlp+ is location of A contains B iff the spatial region occupied by A has the spatial region occupied by B as a part, and B is not part of A. [T] contains interacts with A is connected to B iff there exists a fiat, material or temporal path between A and B. [S][T] core nlp is connected to A is adjacent to B iff there is a small, but non-zero distance between A and B OBO_REL:adjacent_to core nlp is adjacent to is represented by: a relation between an entity and some symbol. is represented by is supported by is a relation between a proposition and something that supports the truth of the assertion. is supported by has disputing evidence is a relation between a proposition and something that disputes (does not directly support) the truth of the assertion. is disputed by is supporting evidence for is disputing evidence for a represents b when a serves as a sign, symbol or model of b. core represents is positionally after is a relation between entities placed on a dimensional axis in which the projection of the position of the first entity is numerically greater than the projection of the position of the second entity. is positionally after A is referred to by B iff B is an informational entity that makes reference to A. is referred to by A has concretization B iff A is an informational entity and B is the a quality of some material entity. has concretization A is concretization of B iff A is a quality of a material entity and B is an informational entity. is concretization of is measurement value of is a relation between a value and the entity that it is a measurement of. is measurement value of has measurement value is a relation between a quality/realizable and a measurement value. core has measurement value has quality is a relation between an entity and the quality that it bears. has quality is quality of is a relation between a quality and the entity that it is a property of. is quality of is source of is a relation between a source of information about some entity. is source of has unit is a relation between a quantity and the unit it is a multiple of. core has unit is unit of is a relation between a unit and a quantity that it is a multiple of. is unit of has property is a relation between an entity and the quality, capability or role that it and it alone bears. has property michel's hair has the quality of being brown in colour. is property of is a relation betweena quality, capability or role and the entity that it and it alone bears. is property of has function is the relation between an entity and a function that is ascribed to it. has function is function of is a relation between a function and an entity that it is a property of. is function of is role of is a relation between a role and the entity that it is a property of. is role of has role is a relation between an entity and a role that it bears. has role has output is a relation between an process and an entity, where the entity is present at the end of the process. core sadi has output has input is a relation between a process and an entity, where the entity is present at the beginning of the process. core sadi has input is input in is a relation between an entity and a process, where the entity is present at the beginning of the process. sadi is input in glucose and ATP are inputs in the hexokinase-mediated conversion of glucose to glucose-6-phosphate. is output of is a relation between an entity and a process, where the entity is present at the end of the process. sadi is output of glucose-6-phosphate and ADP are outputs in the hexokinase-mediated conversion of glucose to glucose-6-phosphate. is implementation of is a relation between an information entity and a specification that it conforms to. is implementation of has implementation is a relation between a specification and an implementation that conforms to it. has implementation has disposition is the relation between an entity and a disposition that it bears. has disposition is disposition of is a relation between a disposition and the entity that it is a property of. is disposition of is positionally before is a relation between entities placed on a dimensional axis in which the projection of the position of the first entity is numerically less than the projection of the position of the second entity. is positionally before is directly after is a relation between entities placed on a dimensional axis in which the projection of the position of the first entity is numerically greater than the projection of the position of the second entity, and the entities are adjacent to one another. is directly after is directly before is a relation between entities placed on a dimensional axis in which the projection of the position of the first entity is numerically less than the projection of the position of the second entity, and the entities are adjacent to one another. is directly before A transitive, symmetric, temporal relation in which one entity is causally related with another non-identical entity. core is causally related with A transitive temporal relation in which one entity was materially formed from another non-identical entity. OBO_REL:derives_from core is derived from a derives to b if and only if a or some part thereof is consumed in the formation of b. derives into a immediately derives into b if and only if a or some significant part thereof is consumed in the formation of b and there are no identifiable intermediate entities between a and b. immediately derives into A non-transitive temporal relation in which one entity is immediately derived from a non-identical entity such that there are no intermediate entities between them. is immediately derived from A transitive, temporal relation in which one process precedes (has occured earlier than) another process. core precedes OBO_REL:preceded_by is preceded by A non-transitive temporal relation in which one process immediately precedes another process, such that there is no interval of time between the two processes. immediately precedes A non-transitive temporal relation in which one process is immediately preceded by another process, such that there is no interval of time between the two processes. is immediately preceded by is reference for is a relation between a document that provides information about an entity. is referenced by has source is a relation between an entity and another entity from which it stems from. has source is annotation of is a relation between some textual entity and the entity that it annotates. is annotation of is annotated with was annotated with has annotation is a relation between an entity and some textual anntotation. has annotation document x is annotated with the keywords 'ontology','semantic web' is variant of: a relationship indicating that two entities are different (by some measure), but either achieve the same objectives in different ways or are permutations of one another (temporal, logical or otherwise) core is variant of has direct part is a relation to specify a part at a particular level of granularity has direct part a car has an engine as a direct part A is prior version of B iff A is a variant of B and B derives from A. is prior version of cites is a relation to refer to by way of example, authority or proof. cites is cited by is a relation from an object that is referred to by way of example, authority or proof. is cited by is similar to is a relation between two entities that share one or more features. is similar to A is subsequent version of B iff A is a variant of B and A derives from B. is subsequent version of is covalently connected to (transitive) has target is a relation between a process and an entity, where the entity is present at the beginning of the process and undergoes a change or transformation in the process. has target is target in is a relation between an entity and a process, where the entity is present at the beginning of the process and undergoes a change or transformation in the process. is target in glucose is a target in the hexokinase-mediated conversion of glucose to glucose-6-phosphate. is weakly interacting with is a symmetric relation between two molecular entities (or any part thereof) that are interacting through some weak force (van der waals, hydrogen bonds, electrostatic interactions) is weakly interacting with (transitive) a is causally related to b iff there is a causal chain of events from a to b is causally related to is direct part of is a relation between a specific part (at some level of granularity) and its whole. core is direct part of is product of is a relation between an entity and a process, where the entity is present at the end of the process as a result of a transformation in the process target. sadi is product of glucose-6-phosphate is the product of the hexokinase-mediated conversion of glucose to glucose-6-phosphate. has product is a relation between an process and an entity, where a new entity exists at the end of the process. sadi has product is component part of is a relation between a component and a whole, where the component is instrinsic to the whole, and loss of the part would change the kind that the whole is. core is component part of A is spatiotemporally related to B iff A is in the spatial or temporal vicinity of B core is spatiotemporally related to A 'is surrounded by' B iff the A 'is contained by' B and A 'is adjacent to' B or A 'is directly connected to' B. is surrounded by A 'surrounds' B iff the A 'contains' B and A 'is adjacent to' B or A 'is directly connected to' B. surrounds A overlaps with B iff there is some C that is part of both A and B. [S][R] overlaps with is about is a relation between an information content entity and the entity that its primary subject. is about is covalently connected to is a relation between an atom and another atom. is covalently connected to is weakly interacting with A relation between an information content entity and a product that it (directly/indirectly) specifies specifies a relation between a product and the information content entity that specifies it. is specified by is manifested as is a relation between an expression and its manifestations. is manifested as the english language version of 'war of the worlds' is manifested as a collection of english language versions of the book. a is causally related from b iff there is a causal chain of events from b to a core is causally related from realizes is a relation between a process and a realizable entity (role, function, disposition). core realizes is realized in the role of a patient is realized in medical examination satisfies is a relation between an entity and the specification or objective that it conforms to. satisfies is satisfied by is created by was created by has creator is a relation between an entity and that which created it. dc:creator has creator the iPhone was created by Apple Inc is created by is creator of is a relation between a creator and an entity.. is creator of has component part is a relation between a whole and a component part where the component is instrinsic to the whole, and loss of the part would change the kind that it is. has component part a human has blood as a component part has expression the story 'war of worlds' is expressed as every language edition of the book 'war of the worlds' is expression of is a relation between more concrete expression of some conceptualization. is expression of every language edition of 'war of the worlds' are expressions of the story of 'war of the worlds' A is broader than B (t) iff for A is broader than B. http://www.w3.org/2004/02/skos/core#narrowerTransitive is broader than (t) A is narrower than B (t) iff for A is narrower than B. http://www.w3.org/2004/02/skos/core#broaderTransitive is narrower than (t) A is generically related with B iff A is an abstract entity or an information content entity and B is a information content entity or a physical entity, respectively. is generically related with is manifestation of A is narrower than B iff the meaning of term A is narrower in scope than the meaning of term B http://www.w3.org/2004/02/skos/core#broader is narrower than http://www.w3.org/2004/02/skos/core#narrower is broader than A is match to B iff A and B are terms with similar (related, broad, close, exact) meanings http://www.w3.org/2004/02/skos/core#relatedMatch is match to http://www.w3.org/2004/02/skos/core#exactMatch is exact match to http://www.w3.org/2004/02/skos/core#closeMatch is close match to http://www.w3.org/2004/02/skos/core#broadMatch is broad match to is dissimilar to is a relation between two entities in which one is considered dissimilar to the other based on some criteria. is dissimilar to is opposite to is a relation between two entities in which one is diametrically opposed to the other. is opposite to hot is the opposite of cold; left is opposite of right is version of is a relation that holds between any two versions in which one is a subsequent or alternate version of (through a branch). is version of has parameter is a relation between a process and an information content entity which modulates the behaviour of some participant. sadi has parameter is parameter in is a relation between a data item and some data transformation process. is parameter in is described by is a relation between one entity and another entity that provides a description (detailed account) of it. is described by is orthologous to is a relation between two biological entities that share a common ancestor and occur in different species. is orthologous to describes is a relation between one entity and another entity that it provides a description (detailed account of). core describes has capability is a relation between an entity and the capability that it bears. has capability SIO has the capability to semantically integrate data. refers to is a relation between one entity and the entity that it makes reference to. core nlp+ refers to is subject of is paralogous to is a relation between two entities which indicates their common ancestry as a result of a gene duplication. is paralogous to mentions references is a relation between one entity and the entity that it makes reference to by name, but is not described by it. core references is model of is a relation between a model (an artifact) and the entity it purports to represent. is model of the architect builds a model that represents the building she envisions. is modelled by a relation between two entities which indicates their common ancestry but due to horizontal gene transfer. is xenologous to has trigger is a relation between a realizable and the factor that causes it to be realized. has trigger is trigger for has basis is a relation between a realizable entity and the quality that forms the basis for it. has basis the solubility of salt (the disposition) is based on the molecular structure of NaCl (the quality) that allows the polarized water-molecules (the trigger) to break the ion bonds (the realization). is base for is a relation between a quality and the realizable entity that it is the basis for. is base for the solubility of salt (the disposition) is based on the molecular structure of NaCl (the quality) that allows the polarized water-molecules (the trigger) to break the ion bonds (the realization). is realizable property of has realizable property is capability of is a relation between a capability and the entity that bears it. is capability of A is directly connected to B iff there exists a path direclty between A and B. is directly connected to A transitive temporal relation in which an entity mainstains identity from one state to another. transforms into A temporal relation in which an entity mainstains identity from one state to another. immediately transforms into A transitive temporal relation in which an entity mainstains identity from one state to another. is transformed from A temporal relation in which an entity mainstains identity from one state to another. is immediately transformed from in relation to is a comparative relation to indicate that the instance of the class holding the relation exists in relation to another entity. core in relation to a relation between an entity and an identifier. has identifier identifies a relation between an identifier and an entity. is identifier for has unique identifier is an inverse functional relation between an entity and an identifier that uniquely identifies it. has unique identifier is unique identifier for is a relation between an identifier and an entity that it uniquely identifies is unique identifier for has time boundary has start time has end time is start time of is end time of exists at is a relation between an entity and a time measurement. core exists at a is mutual disposition of b if and only if the realization of the disposition a necessarily causes the realization of the disposition b. is mutual disposition of is greater than or equal to is a comparison relation between two quantities in which the first has a value larger or equal to the second. is greater than or equal to a is mutually related to b if and only if the realization of the relation of a necessarily causes the realization of a relation to b. is mutually related to a is mutual role of b if and only if the realization of role a necessarily causes the realization of role b. is mutual role of is greater than to is a comparison relation between two quantities in which the first has a value smaller or equal to the second. is lesser than or equal to is greater than to is a comparison relation between two quantities in which the first has a value larger than the second. is greater than is lesser than to is a comparison relation between two quantities in which the first has a value smaller than the second. is lesser than is comparable to is a relation between two entities that share at least one feature whose value can be compared. core is comparable to is numerically comparable to is a comparison relation between two quantities whose datatype value can be compared. is numerically comparable to is equal to is a comparison relation between two quantities whose value are exactly the same. is equal to is inequal to is a comparison relation between two quantities whose value are not the same. is inequal to has evidence is a relation between a proposition and something that demonstrates the truth of the assertion. has evidence is evidence for has evidence is a relation between a proposition and something that refutes (is incompatible with) the truth of the assertion. is refuted by is refuting evidence for measured at is a relation between a measurement value and the time measurement. core measured at a in relation from b is a comparative relation in a is the object of reference in a relation with b. in relation from has frequency is a relation that specifies the occurence of an object or event has frequency is frequency of is a relation between a temporal unit and an object or event is frequency of has substrate is a relation between a process and an object where the object is destroyed by its participation in the process. has substrate is first part of is a proper part relation in which the part is the first of a set of linearly ordered parts resulting from the projection of the whole on a linear coordinate system. is first part of has first part is a proper part relation in which the part is the first of a set of linearly ordered parts resulting from the projection of the whole on a linear coordinate system. has first part has last part is a proper part relation in which the part is the last of a set of linearly ordered parts resulting from the projection of the whole on a linear coordinate system. has last part is last part of is a proper part relation in which the part is the last of a set of linearly ordered parts resulting from the projection of the whole on a linear coordinate system. is last part of has ordered part of is a proper part relation in which the part is one of a set of linearly ordered parts resulting from the projection of the whole on a linear coordinate system. has ordered part is ordered part of is a proper part relation in which the part is one of a set of linearly ordered parts resulting from the projection of the whole on a linear coordinate system. is ordered part of is specialization of is a relation between a more specific instance (in terms of spatial/temporal localization & other attributres) than the other. http://www.w3.org/ns/prov#specializationOf is specialization of a weather forecast for the city of London produced at a specific time is a specialization of a weather forecast for the city of London. is generalization of is a relation between a more general instance (in terms of spatial/temporal localization & other attributres) than the other. is generalization of is alternate of relates two specialized instances. http://www.w3.org/ns/prov#alternateOf is alternate of two weather forecasts for the city of London produced at different times or by different organizations (etc) are alternates of each other, and instances of / specializations of forecasts for the city of London. a is mutual capability of b if and only if the realization of capability a necessarily causes the realization of capability b. is mutual capability of x regulates y if and only if x is a process and y is either a process or a quality, and the progression of x exerts an effect on the frequency, rate or extent of y regulates is regulated by results in is result of affects is affected by is identical to is a relation between two objects that are conceptually the same notwithstanding provenance or other non-intrinsic attributes. is identical to not implemented in standard distribution ovopub is transitively related to has data item is a relation between a dataset and any described / referrenced entity. core has data item 'is data item in' is a relation between an entity that is described or referenced in a dataset. core is data item in has phenotype is a relation between an object and an observable/measurable characteristic. has phenotype is phenotype of is a relation between an observable/measurable characteristic and an object. is phenotype of x positively regulates y if and only if x is a process and y is either a process or a quality, and the progression of x exerts an effect that increases the frequency, rate or extent of y positively regulates x negatively regulates y if and only if x is a process and y is either a process or a quality, and the progression of x exerts an reduced effect on the frequency, rate or extent of y negatively regulates x is associated with y when x and y are logically or statistically related to one another. is associated with x is correlated with y when x holds a statistical relationship with y is correlated with A relation between two objects, in which the first object contains information that is used to produce the second object. encodes an open reading frame encodes a protein (it contains information that specifies the amino acid composition and topology) A relation between two objects, in which the first object is produced from the information contained in the second object. is encoded by a relation between two information content entities in which one is transcribed into (an exact or similar kind) another through some process. is transcribed into DNA is transcribed into RNA is transcribed from is translated into RNA is translated into Protein a relation between two information content entities in which one is translated into (a completely different kind of entity) another through some process. is translated from a relation between two entities which indicates their common ancestry. is homologous to A relation between a informational entity and its actual value (numeric, date, text, etc). core nlp relations sadi has value Every thing is an entity. core entity A material entity is a physical entity that is spatially extended, exists as a whole at any point in time and has mass. core material entity A quality is an attribute that is intrinsically associated with its bearer (or its parts), but whose presence/absence and observed/measured value may vary. core quality A process is an entity that is identifiable only through the unfolding of time, has temporal parts, and unless otherwise specified/predicted, cannot be identified from any instant of time in which it exists. core process+ process A social entity pertains to the interaction among individuals and groups. social entity A social structure is a social entity which consists of relationships between two or more entities. social structure An organization is a collective with a complex articulation of tasks, roles and responsibilities. organization A geographic position is the coordinate of an entity against some geographic coordinate system. geographic position A disposition is the tendency of a capability to be exhibited under certain conditions or in response to a certain stimulus (trigger). core disposition solubility (to dissolve when put in fluid); fragility (disposition to break when dropped) information content entity is an object that requires some background knowledge or procedure to correctly interpret. core ice+ information content entity A role is a realizable entity that describes behaviours, rights and obligations of an entity in some particular circumstance. core role A function is a capability that satisfies some agentive objective, or (evolutionary) optimization. core function A site is a spatial region bounded (in part or in whole) by material entities and may be occupied by material entities. site A nostril; the interior of the heart valve; the interior of a bottle. A material boundary is the boundary of a material entity which exists as a lower dimensional entity at exactly the location where its parts no longer extend into space. Every material entity has a boundary, and a boundary is the boundary of exactly 1 material entity. material boundary the external surface of the window; the surface of the p52 protein An object quality is quality of an object. object quality A process quality is quality that is associated with a process. process quality A sequence is a primary structure descriptor in which each of the letters in the string represents a monomeric unit (residue) in which adjacent letters represent the connectivity between the monomeric units. biopolymer sequence A start date is a time instant pertaining to the date of the beginning of a process. start date An end date is a time instant pertaining to date of the end of a process. end date process status is a process quality that describes the state of a process. process status completed is that status of a process that successfully unfolds. completed ongoing is the status of a process that is not yet complete. ongoing predicted is the quality of an entity that is thought to exist, as evidenced by some rational procedure. predicted physical dimensional quantity A spatial quantity is a quantity obtained from measuring the spatial extent of an entity spatial quantity A quantity that extends in single dimension. 1D extent quantity depth is the dimensional extent into a plane of a 3D projection of the object. depth height is the one dimensional extent along the vertical projection of a 3D object from a base plane of reference. height length is the longer dimensional extent along a 2D projection of the object. length width is the shorter dimensional extent perpendicular to a 2D projection of the object. width thickness is the shortest dimensional extent of a 3D projection of an object. thickness A quantity that extends in two dimensions. 2D extent quantity area is a quantity that pertains to the extent of a two-dimensional surface or shape, or planar lamina, in the plane. area A perimeter is a length of the outline that surrounds a two-dimensional shape. length of perimeter circumference is the length of the outline of a circle or ellipse. it is defined as c = 2*pi*r, where r is the radius. circumference A quantity that extends in three dimensions. 3D extent quantity volume is the quantity of three-dimensional space enclosed by some closed boundary. volume composition quality is a quality that describes its composition or anatomy. compositional quality A quantity is an informational entity that gives the magnitude of a property. quantity shape is the quality of a bearer that relates to its spatial extent. shape A measurement of a spatial location relative to a frame of reference or other objects. position orientation is an angle between the bearer and an axis, or the angle between the bearer and another object. orientation A namespace is an informational entity that defines a logical container for a set of symbols or identifiers. namespace A data item consists of information that has been collected/generated towards some purpose. data item A measurement value is a quantitative description that reflects the magnitude of some attribute. measurement value A coordinate is a measurement of position in n-dimensional space. coordinate A Cartesian coordinate is the signed distance of a point to some referent line. cartesian coordinate A polar coordinate is a position characterized by a distance from a fixed point and an angle from a fixed direction. polar coordinate A unit of measurement is a definite magnitude of a physical quantity, defined and adopted by convention and/or by law, that is used as a standard for measurement of the same physical quantity. unit of measurement A mathematical entity is an information content entity that are components of a mathematical system or can be defined in mathematical terms. math+ mathematical entity A plan is a set of intended actions, through which one expects to achieve a goal. plan A generic name is the preferred name provided by manufacturer. generic name A language entity implements some language specification for the visual interpretation and is part of some document. nlp+ language entity A visual language entity is a language entity that is manifested within the spectrum of light and can be pereceived and processed by a visual system. visual language entity diagram A figure is a graphical entity which consists of a visual (n-dimentional) arrangement of information entities. figure depiction An image is an affine projection of a visual entity to a two dimensional surface. image photo A photograph is an image created by light falling on a light-sensitive surface. photograph chart A statistical graph is a figure that displays the relationship among numeric data and/or mathematical functions. statistical graph A question is a linguistic expression used to make a request for information. question A publication is a document that has been made available by a publisher. publication A record is a document containing a collection of statements about some entity. record data set A dataset is a data item that is a collection of data items. http://www.w3.org/ns/dcat#Dataset dataset A specification is a description of the essential technical attributes/requirements for an object or procedure, and may be used to determine that the object / procedure meets its requirements/attributes. specification effective specification An action specification is a specification composed of a sequence of instructions to achieve some objective. action specification A biopolymer is an organic polymer that are typically produced by the cells of living organisms. biopolymer An algorithm is an effective method expressed as a finite list of well-defined instructions for calculating a function. algorithm A software entity is a computational entity that can be interpreted by or directly executed by a processing unit. software entity A software method (also called subroutine, subprogram, procedure, method, function, or routine) is software designed to execute a specific task. software method A software module is software composed of a collection of software methods. software module A software library is software composed of a collection of software modules and/or software methods in a form that can be statically or dynamically linked to some software application. software library A software application is software that can be directly executed by some processing unit. software application A software interpreter is a software application that executes some specified input software. software interpreter A software script is software whose instructions can be executed using a software interpreter. software script Language is a language entity which is the result of encoding and decoding information through systematic creation and usage of systems of symbols, each pairing a specific sign with an intended meaning, established through social conventions language A symbol is a proposition about what an entity represents. symbol A book is a publication composed of a large number of entries. book A chapter is a document section of a book or thesis. chapter A character is a language symbol used to construct words. character A novel is a fictitious prose narrative of book length, typically representing character and action with some degree of realism. novel A paragraph is a self-contained unit of written discourse consisting of one or more sentences. paragraph A document section is a component of a document. document section A capability is a realizable entity whose basis lies in one or more parts or qualities and reflects possibility of an entity to behave in a specified way under certain conditions or in response to a certain stimulus (trigger). capability+ core capability A sentence is a grammatical unit consisting of one or more words that bear minimal syntactic relation to the words that precede or follow it. sentence A word is the smallest free form (an item that may be expressed in isolation with semantic or pragmatic content) in a language. word An identifier is a label that specifically refers to (identifies) an entity (instance/type). identifier A name is a label used to identify an entity. name A preferred name is the name that is generally used by some organization. preferred name A common name is a name that is commonly used. common name A brand name is a trademarked and marketed name of a product. brand name A scientific name is a name given through scientific nomenclature. scientific name A magazine is a periodical that typically contains essays, stories, poems, etc., by many writers, and often photographs and drawings, frequently specializing in a particular subject or area, as hobbies, news, or sports. http://purl.org/ontology/bibo/Magazine magazine A synonym is a word with the same or very similar meanings. synonym An antonym is a word with opposite or nearly opposite meaning. antonym A hypernym is a term with a broader meaning. hypernym A hyponym is a term with a narrower meaning. hyponym A homonym is a word that sounds the same but has different meaning. homonym A workflow is an algorithm that is is a depiction of a sequence of operations to achieve one or more objectives. workflow An ontology document is a document that contains an ontology. ontology document A pattern is a generalized representation of some repeatable concrete or informational item. pattern A sequence motif is a pattern of nucleotides in a DNA sequence or amino acids in a protein. sequence motif A descriptor (index term, subject term, subject heading) is a term that captures the essence of the topic of a document. descriptor A definition is a description that succintly characterizes an entity. definition A description is language entity in which elements of a language (formal or natural) are used to characterize an entity. description A category is a class of entities having particular shared characteristics. category A class is a collection of sets which can be unambiguously defined by a property that all its members share. class A web service is a software application that can be accessed over a network, such as the Internet, and executed on a remote system hosting the requested services. web service A criterion is a specification to describe properties used for evaluation. criterion An inclusion criterion is a criterion that must be present to satisfy some objective. inclusion criterion An exclusion criterion is a criterion that must be absent to satistify the objective. exclusion criterion A parameter is variable whose value changes the characteristics of a system or a function. parameter A monomer is a submolecule that is proper part of some polymer, and is a building block for such polymer. monomer A keyword is a descriptor in which the association of the word with the entity facilitates information retrieval. keyword A document is a bounded physical or digital representation of a body of information designed with the capacity (and usually intent) to communicate. document A list is any enumeration of a set of items. list A manuscript is a document prior to publication. manuscript A note is a brief document. note A patent is an information entity granted by a patent issuing authority which confers upon the patenter the sole right to make, use and sell an invention for a set period of time. patent An article is a publication that is stand-alone section of a larger work. article A blog is a publication accessible at some website and is typically about various experiences. blog A book volume is a book that is part of a collection. book volume A conference proceedings is a book composed of papers presented at a conference. conference proceedings A book series is a collection of books that have been sequentially published. book series An edited publication is a publication that has been examined and potentially changed by an editor. edited publication A journal is a a peer-reviewed periodical in which scholarship relating to a particular academic discipline is published. http://purl.org/ontology/bibo/Journal journal A manual is a document that instructs on the usage of a device. manual A periodical is a publication that appears on a regular schedule. http://purl.org/ontology/bibo/Periodical periodical A newspaper is a periodical publication containing news regarding current events, informative articles, diverse features, editorials, and advertising. http://purl.org/ontology/bibo/Newspaper newspaper A technical report is a publication published by a school or other institution, usually numbered within a series. technical report A thesis document is the written research component of a post-secondary institution that contains a statement supported by arguments. thesis document An honor's thesis is a thesis prepared as a requirement for an honor's undergraduate degree. honor's thesis A Master's thesis is a thesis prepared as a requirement for a Master's degree. master's thesis A PhD thesis is a thesis prepared as a requirement for a doctoral degree. phd thesis A booklet is a document that lacks a named publisher or sponsoring institution. booklet A diary is a document which describes day-to-day experiences. diary A bibliographic attribute is an attribute related to publications. document component An address is a position that indicates the physical location of some entity using a social convention. address An affiliation is a social relation which indicates the partnership between two or more entities. affiliation A citation is a textual entity which denotes a source described in the bibliography or reference section of a document. citation A document title is a textual entity that summarizes the topic of the document in one sentence. document title A reference is a textual entity that describes a single source used in the preparation or development of the work. reference A page range denotes the start and end page in some document. page range A page total is a textual entity that is about the number of pages in some informational entity. page total a label is a term that is associated with some entity label A language label is a label that denotes the language of a textual entity. language label A first name is a name that denotes a specific individual between members of a group of individuals, whose members usually share the same surname. first name A last name (surname) is a name added to a given name and is part of a personal name and is often the family name. last name full name A personal name is a name to identify an individual person and usually comprises of a first name and a last name. personal name A legal name is a name given at birth, or which appears on their birth certificate, marriage certificate, or change of name certificate. legal name A title is a textual entity that summarily describes some entity. title A document version is a version of a work in some sequence of derivative works. document version An abstract section is a document section that provides brief summary of a document that explains the main argument(s), topic(s) or findings. abstract section An acknowledgements section is a document section that identifies individuals, groups or organizations for their support in the development of the work. acknowledgements section An author contribution section is a document section that describes the contribution of the authors. author contribution section An author section is a document section that lists the contributing authors. author section A bibliography section is a document section that is composed of a list of references used in the development of the work. bibliography section A copyright section is a document section that contains a notice of copyright. copyright section A correspondence section is a document section that contains the details for contacting the corresponding author. correspondence section The discussion section is a document section containing a summary of the findings, a reflection on the significance of findings, comparison with related work, among others. discussion section An introduction section is a document section that generally provides background, motivation and goals of the work. introduction section The materials and methods section is a document section containing a description of the materials and methods used in the study. materials and methods section The materials section is a document section containing a description of the materials used in the study. materials section The methods section is a document section containing a description of the methods used in the study. methods section The results section is a document section describing the main findings of the study. results section The table of contents is a document section that lists all sections (and optionally subsections) in a sequential order along with their page number. table of contents Implication is a logical operator that holds between a set T of propositions and a proposition B, when every model (or interpretation or valuation) of T is also a model of B. implies (->) A namespace label is a short name for a namespace. namespace label A logical operator is a unary or binary relation to construct logical expressions. logical operator AND is a logical operator that has the value true if both of its operands are true, otherwise a value of false. conjunction (and) A proposition is a sentence expressing something true or false. proposition A dimensionless quantity is a quantity that has no associated unit. dimensionless quantity A dimensional quantity is a quantity that has an associated unit. dimensional quantity An argument is a set of one or more declarative sentences (or propositions) known as the premises along with another declarative sentence (or proposition) known as the conclusion. argument A premise is a proposition of an argument from which the conclusion is drawn. premise A conclusion is a proposition which is reached after considering the evidence, arguments or premises. conclusion A deductive argument is an argument that asserts that the truth of the conclusion is a logical consequence of the premises. deductive argument An inductive argument is an argument that asserts that the truth of the conclusion is supported by the premises. inductive argument A sound argument is a valid argument with true premises. sound argument A valid argument is an argument where the truth of the conclusion is a logical consequence of the premises and (consequently) its corresponding conditional is a necessary truth. valid argument An invalid argument is an argument where the truth of the conclusion is false because it is not a logical consequence of the premises. invalid argument truth value is a quality of information that is claimed/verified to be true or false. truth value true is a truth value that indicates that it holds under all possible worlds. true true false is a truth value in that indicates that it is not true. false false A term is a word or phrase used to denote one or more entities. term An emotion is a process (experience) that arises internally or from an involuntary physiological response to a stimulus. emotion++ emotion mass is the quality of the amount of substance. mass OR is a logical operator that results in true whenever one or more of its operands are true. disjunction (or) NOT is a logical operator in that has the value true if its operand is false. negation (not) XOR, also called exclusive disjunction or (symbolized XOR, EOR, EXOR, or ⊕), is a type of logical disjunction on two operands that results in a value of true if exactly one of the operands has a value of true. exclusive disjunction (xor) A hypothesis is a proposed explanation for a phenomenon. hypothesis An academic organization is a lawfully recognized organization that confers diplomas, degrees and other forms of recognition of academic achievement. academic organization A social relation is a social entity that describes a relationship between two or more individuals or groups. social relation A set is a collection of entities, for which there may be zero members. set A university is an institution of higher education and research which grants academic degrees in a variety of subjects and provides both undergraduate education and postgraduate education. university A collection of documents is a non-zero set of documents. http://purl.org/ontology/bibo/Collection collection of documents 2 A website is a collection of documents published on the World Wide Web. website film moving pictures A movie is a series of images that are displayed in rapid succession to give the impression of movement. movie An excerpt is a contiguous or discontiguous portion of a document. excerpt A quote is a excerpt that is attributed to a particular source. quote A geographic image is a photograph of some geographical area. geographic image A web page is a document that is published according to World Wide Web standards. web page Email message is a digital document that is composed of a header and a body and is transmitted using the SMTP protocol. email process number is a number associated with a process that denotes its ordinal position in a set of processes. process number A letter is a document that contains a personal communication from one part to another. letter normality is the quality in which the value may differ from normal or average normality An edition number is count of a literary work edited and published, as by a certain editor or in a certain manner including being printed during some interval of time. edition number volume number is a count of a sequence of periodicals. volume number A polymer is a molecule composed of a connected set of monomeric residues. polymer A functional specification is a specification that describes the characteristics of an object. functional specification A design specification is a specification that provides precise and explicit information about the requirements for a product design. design specification A specification for spatial location is an effective specification towards representation spatial position or spatial data. spatial specification Longitude is a geographic position that refers to the angle east or west of a reference meridian between the two geographical poles to another meridian that passes through an arbitrary point. longitude Latitude is a geographic coordinate which refers to the angle from a point on the Earth's surface to the equatorial plane latitude A coordinate system is a specification for spatial location that uses a set of numbers, or coordinates, to uniquely determine the position of a point or other geometric element. coordinate system A Cartesian coordinate system specifies each point uniquely in a plane by a pair of numerical coordinates, which are the signed distances from the point to two fixed perpendicular directed lines, measured in the same unit of length. cartesian coordinate system A concept is term that refers to a generalization of a set of attributes or entities. concept A polar coordinate system is a two-dimensional coordinate system in which each point on a plane is determined by a distance from a fixed point and an angle from a fixed direction. polar coordinate system A positional description is a description of location using some system or frame of reference. positional identifier A cylindrical coordinate system is a three-dimensional coordinate system that specifies point positions by the distance from a chosen reference axis, the direction from the axis relative to a chosen reference direction, and the distance from a chosen reference plane perpendicular to the axis. cylindrical coordinate system A spherical coordinate system is a coordinate system for three-dimensional space where the position of a point is specified by three numbers: the radial distance of that point from a fixed origin, its polar angle measured from a fixed zenith direction, and the azimuth angle of its orthogonal projection on a reference plane that passes through the origin and is orthogonal to the zenith, measured from a fixed reference direction on that plane. spherical coordinate system An OWL ontology is an ontology as specified by the W3C OWL specification. OWL ontology A 3D cartesian coordinate is a coordinate that is composed of an x, y and z coordinate. 3D cartesian coordinate 1 1 1 An objective is a proposition that indicates a planned or anticipated outcome. objective A realizable entity is an attribute that is exhibited under some condition and is realized in some process. core realizable entity A term variant is a term that is a variant of another term. term variant to modify is the capability to change some entity. to modify to record is the capability to detect and transcribe information in a specified format on some physical medium. to record http://purl.obolibrary.org/obo/OBI_0000368 to magnify is the capability to increase the appearance of the size of an object. to magnify to heat is a capability to increase the internal kinetic energy of a material. to heat to cool is the capability to decrease the internal kinetic energy of a material. to cool http://purl.obolibrary.org/obo/OBI_0000387 to freeze is the capability to decrease the internal kinetic energy of a material such that it changes state from a gas or liquid to a solid. to freeze http://purl.obolibrary.org/obo/OBI_0000375 to separate is the capability to i) distinguish some entities based on some attribute(s) and ii) subsequently physically displace them. to separate to ionize is the capability to physically convert an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions. to ionize to supply energy is the capability to transfer energy from a source to a sink. to supply energy to observe is the capability to watch attentively. to observe dysfunction is a capability to act in a manner that is abnormal or opposite to the object's typical function. dysfunction fitness is the quality of an object with respect to some stated functions or evolutionary adaptation. fitness intent is a desire to realize a particular outcome. intent purpose is the reason for which something is done or created or for which something exists. purpose A belief is a proposition that is believed to be true. belief rank 0 tensor A number is a tensor of rank 0. number A variable is a value that may change within the scope of a given problem or set of operations. variable An equation is a mathematical statement that asserts the equality of two expressions. equation region A spatial region is an object contained in some region of space. spatial region The airspace above Ottawa airport; the band around the northern hemisphere between 50 degrees N and 60 degrees N; the spatial region occupied by a bottle. to measure is the capability to obtain information about some entity by examining its attributes in relation to some reference metric. to measure to inject is the capability to administer a substance into some object through its external barrier. to inject to boil is the capability to increase the internal kinetic energy of a material such that it changes state from a solid or liquid to a gas. to boil to reduce energy is the capability to remove energy from a source. to reduce energy to supply electricity is the capability to transfer electricity from a source to a sink. to supply electricity to change appearance is the capability to change the material composition of an object. to change materially to demagnify is the capability to decrease the appearance of the size of an object. to demagnify to change appearance is the capability to change the visual attributes of an object. to change appearance perception is the organization, identification, and interpretation of sensory information in order to fabricate a mental representation through the process of transduction, which sensors in the body transform signals from the environment into encoded neural signals. perception to contain is the capability to bound or constrain a physical entity in some site. to contain to immobilize is the capability to contain an entity in such a way that it may not move in space. to immobilize to filter is the capability to retain certain entities based on selected attribute(s) while allowing other entities to pass through. to filter to excite is the capability to supply energy to a materila by bombarding it with energetic particles (e.g., photons). to excite to emit is the capability to release some physical entity (light, pollution, etc). to emit to change energetically is the capability to change the energetic aspects of an object. to change energetically to positively charge is the capability to remove an electron or add a positively charged ion to a chemical entity. to positively charge to negatively charge is the capability to add an electron or negatively charged ion to a chemical entity. to negatively charge to assemble is the capability to combine entities together into a larger object that persists in time. to assemble to extract is the capability to remove certain entities based on selected attribute(s) while allowing other entities to remain. to extract to transport is the capability to displace a material from one location to another. to transport time measurement is a measurement value of the duration of some interval of time or a particular instant of time (against some frame of reference). Time intervals are specified as date/datetime ranges. time measurement the duration of my life; the duration of a surgical procedure, the moment of death to change spatially is the capability to affect the physical movement of some entity. to change spatially A patient is an individual that is the recepient of medical care. patient A doctor is an individual who practices medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury, and other physical and mental impairments. doctor to modulate to regulate is to control or maintain the rate or speed of an object or process. to regulate A file is an information-bearing object that contains a physical embodiment of some information using a particular character encoding. http://www.w3.org/ns/dcat#Distribution file to provide is the capability to make available some object to another that requires it. to provide A nurse is an individual that is involved in the protection, promotion, and optimization of health and abilities, prevention of illness and injury, alleviation of suffering through the diagnosis and treatment of human response, and advocacy in the care of individuals, families, communities, and populations. nurse A study subject is an individual that is the subject of the study. study subject An x cartesian coordinate is the coordinate of an object onto the x-axis of a cartesian coordinate system. x cartesian coordinate An y cartesian coordinate is the coordinate of an object onto the y-axis of a cartesian coordinate system. y cartesian coordinate A z cartesian coordinate is the coordinate of an object onto the z-axis of a cartesian coordinate system. z cartesian coordinate A study group is a group of individuals that are subjects in an observational or intervention study. study group A professor is an individual that is a scholarly teacher. professor A student is an individual who is attends an educational institution. student An academic is an individual that participates in education and scholarship. academic to increase the rate of formation is to regulate the rate of formation in a manner that increases this rate relative to a reference process. to increase the rate of formation to investigate is the capability to uncover facts. to investigate A mutual disposition is a disposition that simulataneously invokes another disposition when realized. mutual disposition anger is disgust directed toward an equal status individual. anger Hate is a deep and emotional extreme dislike, directed against a certain object or class of objects. hate love is an emotion of a strong affection and personal attachment. love A geolegal region is a geographic region which has causal powers confered by a legal entity. geolegal region The 50 kph zones in Ottawa; the geographic region occupied by France. A geographic region is a spatial region whose boundaries are typically defined against some material frame of reference (like the earth). geographic region The spatial region occupied by the province of ontario; the spatial region occupied by a lake. a geopolitical region is a geographic region recognized by social or legal convention. geopolitical region The geographic region bounded by Canada; the spatial region occupied by the US embassy in Ottawa. A time internval is a contiguous temporal region having some duration. time interval A time instant is a temporal region which occurs instantaneously, e.g. having no duration. time instant at this moment; the moment at which a finger is detached in an industrial accident; the moment at which a child is born; the moment of death A table is a figure that consists of an ordered arrangement of columns and rows. table scatter chart scatter diagram scatter graph A scatterplot is a statistical graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis. scatterplot A year is a period of time taken by a planet to make one revolution around the sun. year A month is a period of time that divides the year. month A day is a period of 24 hours. day A century is a period of one hundred years. century A millenium is a period of 1000 years millennium An hour is a period of 60 minutes. hour A minute is a period of 60 seconds. minute A second (symbol: s) is the base unit of time in the International System of Units (SI) and is the second division of the hour by sixty, the first division by 60 being the minute. second An informational quality is a quality that pertains to information. informational quality A 2D cartesian point is a point whose position is specified along two dimensions using Cartesian coordinates. 2D cartesian point 1 1 Altitude is a distance above sea level. altitude The center of mass (aka barycenter) is the weighted average location of all the mass in a body or group of bodies. center of mass A 3D cartesian point is a point whose position is specified along three dimensions using Cartesian coordinates. 3D cartesian point 1 1 1 A 1D cartesian point is a point whose position is specified along a single dimension using Cartesian coordinates. 1D cartesian point 1 line chart A line graph is a statistical graph in which lines contains the evaluation of functions or individual points connected by line segments. line graph Graph 1 in http://tinyurl.com/opwnvm A bar graph is a statistical graph with rectangular bars of lengths proportional to that value that they represent. bar graph Graphs 3,4,5 in http://tinyurl.com/opwnvm A horizontal bar graph is a bar graph in which the rectangular bars are horizontally oriented in space. horizontal bar graph Graph 3 in http://tinyurl.com/opwnvm A vertical bar graph is a bar graph in which the rectangular bars are vertically oriented in space. vertical bar graph Graph 4,5 in http://tinyurl.com/opwnvm A stacked bar graph is a bar graph in which each rectangular bar is partioned by the categorical value of each series of data. stacked bar graph Graphs 6,7 in http://tinyurl.com/opwnvm A line-bar graph statistical graph that contains both lines and bars. line-bar graph Graph 8 in http://tinyurl.com/opwnvm A figure part is a part of a figure. figure part A plot is a part of a figure that corresponds to the spatial region between the set of axes. plot The square portion of the chart bounded by lines that overlap with the two axes in Graph 1 of http://tinyurl.com/opwnvm An axis is a line segment that is part of a statistical graph in which the position along the line corresponds to a numeric or categorical value. The value of a plotted geometric objects (e.g. point) can be obtained from the perpendicular projection of the position of the object onto the axis. Axis may also be associated with a textual description of what the values on the axis represents. axis The left vertical and bottom horizontal lines with tickmarks in Graph 1 http://tinyurl.com/opwnvm A Cartesian coordinate axis is an axis whose behavior follows that of a Cartesian coordinate system. Cartesian coordinate axis horizontal axis An x-axis is a Cartesian coordinate axis that is aligned with the horizon. In most figures, this axis represents categories, such as months, market segments, or other non-numeric data. x-axis The horizontal axis in http://tinyurl.com/opwnvm vertical axis A y-axis is a Cartesian coordinate axis that is spatially oriented perpendicular to the x-axis. y-axis A z-axis is a Cartesian coordinate axis that is spatially oriented normal to the plane formed by the x- and y-axes. z-axis A category axis is an axis in which the position along the line is partioned into categories. category axis The horizontal axis corresponding to months of the year in graph 4 of http://tinyurl.com/opwnvm A primary category axis is a category axis that either defines the sole value range or holds the larger set of categorical values specified by the secondary category axis. primary category axis The category axis that corresponds to years in Graph 1 of http://tinyurl.com/opwnvm A secondary category axis is a category axis that defines a finer granular part (or subset) of the value range of the primary category axis. secondary category axis The category axis that corresponds to months in Graph 1 of http://tinyurl.com/opwnvm A value axis is an axis in which the position along the line is partioned into numeric values. A value axis holds the properties of having a minimum and a maximum value, and is usually associated with tickmarks that indicate intervals along the axis. value axis The value axis that ranges from 3.0 to 7.4 and corresponds to billions of dollars in Graph 1 of http://tinyurl.com/opwnvm A left value axis is a value axis that is spatially positioned to the left of the plot area. left value axis The value axis that ranges from 3.0 to 7.4 and corresponds to billions of dollars in Graph 1 of http://tinyurl.com/opwnvm A right value axis is a value axis that is spatially positioned to the right of the plot area. right value axis A scaled value axis is a value axis in which the value range was subject to a mathematic transformation. scaled value axis A linear value axis is a value axis that corresponds to a scaling factor of 1 of the value range. linear value axis A logarithmic value axis is a scaled value axis that corresponds to a scaling factor of the logarithm of the value range. logarithmic value axis A data series is a data set composed of related values displayed in a statistical graph. data series Example: The two series that correspond to "Seasonally adjusted" and "Trend" are composed of the seasonally adjusted value of permits in each month and values from a trend derived from some mathematical tranformation across those values, respectively, in Graph 1 of http://tinyurl.com/opwnvm A data point is a point that which corresponds to the projection of the values of measurement data against the axes of a statistical graph. data point A global maximum stationary point is a data point that corresponds to a measurement value is larger than that of all other plotted datapoints. global maximal stationary point A global minimum data point is a data point that corresponds to a measurement value is smaller than that of all other plotted datapoints. global minimal stationary point A legend is a part of a figure that associates textual descriptions with symbols pertaining to plotted entities. legend The colored line segments and the adjacent textual descriptions in Graph 1 of http://tinyurl.com/opwnvm A graph title is a title that describes a graph. graph title Total value of permits increased slightly in December" in Graph 1 of http://tinyurl.com/opwnvm A primary title is a title that should be first used in describing some entity. primary title subtitle, alternative title A secondary title is a title of lesser importance that should be used after the first title in describing some entity. secondary title scientific data is data obtained from some scientific procedure. scientific data A primary graph title is a primary title that describes a statistical graph. primary graph title "Total value of permits increased slightly in December" in Graph 1 of http://tinyurl.com/opwnvm A secondary graph title is a secondary title that describes a statistical graph. secondary graph title A biological quality is a quality held by a biological entity. biological quality cellular quality is the quality of a cell cellular quality A sequence variant role is a comparative role in which the composition of characters in a sequence differs when compared to another entity of similar type. sequence variant role A variant role is a comparative role in which the value of an attribute differs when compared to another entity variant role An insertion variant role is the role of an sequence that contains a sub-sequence that is considered to be an addition relative to the frame of reference. insertion variant role A deletion variant role is the role of an sequence that lacks a sub-sequence relative to the frame of reference. deletion variant role A phrase is a group of words functioning as a single unit in the syntax of a sentence. phrase 2 A human is a primates of the family Hominidae and are characterized by having a large brain relative to body size, with a well developed neocortex, prefrontal cortex and temporal lobes, making them capable of abstract reasoning, language, introspection, problem solving and culture through social learning. human A mouse is a small mammal belonging to the order of rodents, characteristically having a pointed snout, small rounded ears, and a long naked or almost hairless tail. mouse A rat is a medium-sized, long-tailed rodent of the superfamily Muroidea. rat A worm is a non-arthropod invertebrate animal that typically have a long cylindrical tube-like body and no legs. worm Escherichia coli (e coli) is a Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms. e.coli to consume is the capability to internalize a material entity. to consume A clause consists of a subject and a predicate. clause to actively interact with is the capability to interact with another entity in a way that requires physical contact. to actively interact with A person is an object that has certain capacities or attributes constituting personhood. person to decrease the rate of formation is to regulate the rate of formation in a manner that decreases this rate relative to a reference process. to decrease the rate of formation A polygon vertex is a terminal point at which two polygon edges meet and are part of a polygon. polygon vertex 2 1 A polygon edge is a line segment joining two polygon vertices. polygon edge 2 A polyhedral skeleton is a collection of polygon edges. polyhedral skeleton A polygonal face is a polygon bounded by a circuit of polygon edges, and includes the flat (plane) region inside the boundary. polygonal face A polyhedral surface is composed of polygonal faces. polyhedral surface A polygon is a planar entity that is bounded by a closed path or circuit, composed of a finite connected sequence3 of straight line segments. polygon A geometric entity is an information content entity that pertains to the structure and topology of a space. geometry+ geometric entity A point is a geometric entity that is located in a zero-dimensional spatial region and whose position is defined by its coordinates in some coordinate system. point An endpoint is a terminal point that is the last of an ordered pair of points. endpoint A start point is a terminal point which is the first of an ordered pair of points. start point A model is a representation of some thing. model A line is curve that extends in a single dimension (e.g. straight line; exhibits no curvature), and is composed of at least two fully connected points. line A line segment is a line and a part of a curve that is (inclusively) bounded by two terminal points. line segment 2 A tick mark is a line segment that is spatially positioned perpendicular to the axis of a statistical graph and indicates the position of a specific numeric value (which may be indicated by an adjacent value label) on a value axis, or is one of a pair of tick marks that delineates the boundary of a categorical value (which may be indicated by an adjacent category label) on the categorical axis. tick mark A major tick mark is a tick mark that indicates the position of a specific numeric value and is adjacent to its value label on the value axis, or is one of a pair of tick marks that delineates the boundary of a categorical value indicated by an adjacent category label on the categorical axis. major tick mark A minor tick mark is a tick mark that indicates the position of a specific numeric value but has no adjacent value label, or is one of a pair of tick marks that delineates the boundary of a categorical value but has no adjacent category label on the categorical axis. minor tick mark A ray is a line which that is bounded by a startpoint and extends outwards infinitely along one dimension. ray A quadrilateral is a polygon with composed of four points and four line segments, in which each point is fully connected to two other points. quadrilateral A rectangle is a quadrilateral in which one pair of line segments are parallel and the other pair are perpendicular to the first pair. rectangle A bar is a rectangle that is located in the plot of a statistical graph in which its length is proportional to the values that it represents. bar A triangle is a polygon composed of three points and three line segments, in which each point is fully connected to another point along through the line segment. triangle A directed line segment is a line segment that is contained by an ordered pair of endpoints (a start point and an endpoint). directed line segment 1 1 An arrowed line is a directed line segment in which one or both endpoints is tangentially part of a triangle that bisects the line. arrowed line segment 2 A single arrowed line is directed line in which the endpoint is tangentially part of a triangle that bisects the line. single arrowed line segment 1 A double arrowed line is an arrowed line in which both terminal points are tangentially part of different triangles that bisect the line. double arrowed line segment 2 A horizontal line is a line that is positionally oriented with the horizon. horizontal line A vertical line is a line that is positionally oriented perpendicular to the horizon. vertical line A trend line is a line, line segment or ray that is part of a statistical graph which indicates a statistical or visual direction across categorical or value data. trend line An increasing line is a line segment in which the startpoint and endpoint are ordered along one dimension and the difference of values in a second dimension is positive. increasing line An decreasing line is a line segment in which the startpoint and endpoint are ordered along one dimension and the difference of values in a second dimension is negative. decreasing line An plateau line is a line segment in which the startpoint and endpoint are ordered along one dimension and the difference of values in a second dimension is zero. plateau line A drop line is a statistical graph line that vertically or horizontally connects a data series line with a value axis in a statistical graph. drop line A terminal point is a point that defines the finite extension of a line. terminal point A surface normal is a vector that is perpendicular to a flat surface. surface normal A positionally oriented line is a line that is positioned against some axis of reference. positionally oriented line A statistical graph line is a line used in a statistical graph to communicate some trend or feature of the embedded data. statistical graph line to regulate the rate of formation is to modify the rate at which an object is formed. to regulate the rate of formation curvature is a quality of a bearer that relates to the presence of curves, bends, or angles. curvature straight is a quality of a bearer that is free of curves, bends, or angles. straight PATO:0002180 [for material entities] An infinite line is a line that extends outwards in both directions of a single dimensional and is not bounded by terminal points. infinite line A vector line is a line which that is bounded by a startpoint and extends outwards along one dimension. vector line A vertext normal is the normalized average of the surface normals of the faces that contain that vertex. vertex normal to serve as is the capability to act in a manner corresponding to some role. to serve as to serve as host is the capability to act in a manner that provides hospitality, serves to harbour an organism in or on itself. to serve as a host to infect is the capability to administer a disease-causing organism into some object. to infect polygonal chain, polygonal curve, polygonal path, piecewise linear curve A polyline is a connected sequence of line segments. polyline 2 A collection of points is a geometric entity that contains a non-zero set of geometric points. collection of points to cause disease is the capability to materially change a biological object in that it functions abnormally. to cause disease to activate to reduce the activation energy is to require a smaller amount of energy in order to form or break a chemical bond. to reduce the activation energy to inhibit to increase the activation energy is to require a larger amount of energy in order to form or break a chemical bond. to increase the activation energy to change the activation energy is to change the amount of energy required to form or break a chemical bond. to change the activation energy A quality that has a value that is normal or average. PATO:0000461 normal A quality that has a value that is outside normal or average. abnormal A lipid residue is a part of an organic molecule that was derived from a lipid molecule. lipid residue chemical synthesis is synthesis of a chemical entity from physical precursors through one or more chemical interactions or reactions. chemical synthesis A molecular orbital (or MO) is a mathematical function describing the wave-like behavior of an electron in a molecule. molecular orbital passive transport is the movement of a substance across a membrane and does not require chemical energy. passive transport diffusion is motion of particles at temperatures above absolute zero. diffusion A diffusion equation describes density fluctuations in a material undergoing diffusion. diffusion equation A movement equation describes the displacement of an object in space over time. movement equation An ordinary differential equation (ODE) is a differential equation in which the unknown function (also known as the dependent variable) is a function of a single independent variable. ordinary differential equation A partial differential equation (PDE) is a differential equation in which the unknown function is a function of multiple independent variables and the equation involves its partial derivatives. partial differential equation A differential equation is a mathematical equation for an unknown function of one or several variables that relates the values of the function itself and its derivatives of various orders. differential equation movement is the process in which an object is spatially displaced. core movement Brownian motion is the seemlingly random movement of particles suspended in a fluid. brownian motion osmosis is the movement of water molecules through a selectively-permeable membrane down a water potential gradient. osmosis passive movement is the process in which an object is spatially displaced without an expenditure of energy contained in molecular bonds. passive movement active movement is the process in which an object is spatially displaced using some chemical energy. active movement transporting is a process in which one object physically moves another object from one location to another. transporting membrane transport is the movement of molecules across a membrane. membrane transport primary active transport, also called direct active transport, directly uses energy to transport molecules across a membrane. primary active transport secondary active transport or co-transport uses electrochemical potential difference created by pumping ions out of the cell to transport molecules across a membrane. secondary active transport symport enabled secondary active transport is a secondary active transfort in which both ion and molecule are transported in the same direction simultaneously. symport enabled secondary active transport antiport enabled secondary active transport is a secondary active transfort in which both ion and molecule are transported in opposite directions simultaneously. antiport enabled secondary active transport The self-propelled movement of an object. GO:0040011 locomotion birthing is the process by which a biological organism is brought into existence. birthing dying is a process in which a biological entity ceases to exist. dying An idea is a proposition about some object of conceptual thought. idea biological reproduction is the biological process by which one or more biological organisms are produced from their "parents". biological reproduction creation development formulation production synthesis creating is the process in which an entity comes into existence. creating regulation regulating is a process that modulates the attributes of an object or process. regulating biosynthesis is the synthesis of an organic compound in a living organism, usually aided by enzymes. biosynthesis destruction destroying is a process in which something is broken down and/or ceases to exist. destroying chemical destruction is destruction of a chemical entity to its chemical constituents through one ormore chemical interactions or reactions. chemical destruction interacting is a process characterized by the interaction between two or more entities. core interacting 2 2 data transformation is the process of applying an algorithmic procedure to some input data and producing some output data. data transformation A parameterized data transformation is a data transformation whose behaviour may be modified by one or more parameters. parameterized data transformation A data storage device is a device that is capable of storing information. data storage device A solid-state drive (SSD) is a data storage device that uses solid-state memory to store persistent data. solid state hard drive A hard disk drive (HDD) is a non-volatile, random access device for digital data. It features rotating rigid platters on a motor-driven spindle within a protective enclosure. Data is magnetically read and written on the platter by read/write heads that float on a film of air above the platters. hard disk drive structure is the specification that refers to the composition and arrangement of parts of an object. structure A computational entity is an information content entity operated on using some computational system. computational entity A sound wave is a mechanical wave that is an oscillation of pressure transmitted through a solid, liquid, or gas, composed of frequencies within the range of hearing. sound wave A curve is a geometric entity that may be located in n-dimensional spatial region whose extension may be n-dimensional, is composed of at least two fully connected points and does not intersect itself. curve regulation of a process is a process that modulates the duration, frequency, spatial extent of a target process. regulation of process regulation of capability is the regulation of the ability of one party by another. regulation of capability the regulation of the enzymatic activity. regulation of catalytic capability A representation is a entity that in some way represents another entity (or attribute thereof). representation offset A ordinal position is a number that designates the position of an entity from the first entity in an ordered sequence of entities. ordinal position An attribute is a characteristic of some entity. core attribute A collection is a set for which there exists at least one member, although any member need not to exist at any point in the collection's existence. collection An empty set is a set for which there are exactly 0 members. empty set 0 A standard is a socially-agreed upon specification. standard A regulatory authority is an organization responsible for exercising regulatory or supervisory capacity in some area of human activity. regulatory authority group A collective is a group of entities that share or are motivated by at least one common issue or interest, or work together on a specific project(s) to achieve a common objective. collective A formal specification is a mathematical description of software or hardware that may be used to develop an implementation. formal specification An RDFS ontology is an ontology that conforms to the syntax and semantics of the Resource Description Framework Schema (RDFS). RDFS ontology An OBO ontology is an ontology document as specified by the Open Biological Ontology community. OBO ontology chemical group A chemical functional group is a submolecule that confers specific chemical properties. chemical functional group chemical structure is the structure of a chemical entity in terms of its molecular geometry and electronic structure. chemical structure molecular geometry molecular structure is the spatial arrangement of atoms in a molecule and the chemical bonds that hold the atoms together. molecular structure A probability measure is quantity of how likely it is that some event will occur. probability measure to passively interact with is the capability to interact with another entity in a way that does not require physical contact. to passively interact with A quality that has a value that is increased compared to normal or average. PATO:0002300 increased A process model is a representation of some process. process model An object model is a representation of an object. object model information processing is a process that involves the generation or use of information. information processing A wave is a physical entity that travels through space and time, consist of oscillations or vibrations and may be accompanied by the transfer of energy. wave A textual entity is language entity that is manifested as a sequence of one or more distinct characters. textual entity A version label is a label for a particular form or variation of an earlier or original type. version label A software version label is a version label for a piece of software. software version label major.minor[.build[.revision]] A hole is a site that is opening into or through something. hole A province is a territorial unit, almost always an administrative division, within a country or state. province A state is a set of governing and supportive institutions that have sovereignty over a definite territory and population. state A territory is a non-sovereign geographic region. territory A country is a region legally identified as a distinct entity in political geography. country A city is a relatively large and permanent settlement. city A township is a rural or sub-urban settlement. township software execution is the process of executing software on a computing device. software execution A start time is a time instant pertaining to the time at which a process begins. start time An end time is a time instant pertaining to the time at which a process ends. end time A unique identifier is an identifier that uniquely identifies some thing. unique identifier A social role is a role that is ascribed to individuals in a community. social role A processual role is a role that can only be realized in a process. processual role An abstract role is a role whose basis lies in spatial/temporal or comparative relations. abstract role A justification is a proposition that defends, explains or excuses some argument. justification An academic department is a division of a university or school faculty devoted to a particular academic discipline. academic department institute is a society or organization having a object or common factor, and is normally applied to those with a scientific, educational, or social objective. institute to be a part of is the capability to be assembled into a larger structure that persists in time. to be a part of to associate is the capability to physically interact with another object. to associate to be actively interacted with is the capability to be manipulated by some device or agent. to be actively interacted with A corporation is an organization that is granted a charter recognizing it as a separate legal entity. corporation to be passively interacted with is the capability of an object to be observed. to be passively interacted with to be recorded is the capability of an object to be observed in such a way that information about it can be transcribed in a specified format on some physical medium. to be recorded to be observed is the capability of an object to be perceived. to be observed to disassemble is to physically separate the parts of an object. to disassemble to disassociate is to cease or break association with some thing. to disassociate to interact with is a capabililty that involves another object. to interact with to be interacted with is the capability of an object to be target of a physical interaction. to be interacted with evolving is a process that elicits change across successive generations in the inherited characteristics of biological populations. evolving A positional role is an abstract role which holds by comparing position to another object of reference. positional role A specification of an object, manifested by an agent, intended to accomplish goals, in a particular environment, using a set of primitive components, satisfying a set of requirements, subject to constraints. design An occupational role is a social role that pertains to an organizational structure. occupational role A student role is the role of an individual that is enrolled in courses at an academic institution. student role A professor role is the role of an individual that is involved in teaching of students (undergraduate and/or graduate) at a post-secondary academic institution. professor role An academic role is a social role that pertains to the academic institution. academic role A medical role is the role of an individual that is a participant in the delivery of medical care. medical role physician A doctor role is the role of an individual who practices medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury, and other physical and mental impairments. doctor role A nurse role is the role of an individual that is involved in the protection, promotion, and optimization of health and abilities, prevention of illness and injury, alleviation of suffering through the diagnosis and treatment of human response, and advocacy in the care of individuals, families, communities, and populations. nurse role A patient role is the role of an individual that is the recepient of medical care. patient role A medical practioner is an individual that provides medical care. medical practitioner A dentist role is the role of an individual that that specializes in the diagnosis, prevention, and treatment of diseases and conditions of the oral cavity. dentist role to move to translocate is the capability to displace oneself from one location to another. to translocate to be moved to be translocated is the capability to be physically displaced from one location to another to be translocated A comparative role is an abstract role which holds by comparing some attribute of another object of reference. comparative role to be compared is the capability of an object to be examined in order to note the similarities or differences among a set of objects. to be compared to compare is the capability to examine in order to note the similarities or differences among a set of objects. to compare to examine is the capability to make detailed observation. to examine to be examined is the capability of an object to be observed in a detailed manner. to be examined An administrative role is the role of an individual that performs administrative tasks for some organization. administrative role A secretary role is the role of an individual that performs administrative tasks to support one or more individuals of the same organization. secretary role A chemical identifier is an identifier for a chemical entity chemical identifier A record identifier is an identifier for a database entry. record identifier A physical entity identifier is an identifier for a physical entity. physical entity identifier An informational entity identifier is an identifier for an informational entity. informational entity identifier A molecular identifier is an identifier for a molecular entity. molecular identifier planning is the agentive process of developing a plan that specifies a set of actions in order to meet a set of goals or objectives. planning A curve segment is a part of a curve that consists of at least three points. curve segment A stationary point is a point that is part of a curve in which the derivative at that point is zero, and hence its value is at least a local maximum or minimum. stationary point A local maximum stationary point is a point that has a higher value in some axis than adjacent points. local maximum stationary point A local minimum stationary point is a point that has a lower value in some axis than adjacent points. local minimum stationary point learning is the agentive process of acquiring knowledge. learning comparison comparing is the process of examining a set of objects and determining their equality or inequality based on one or more features. comparing reasoning is the agentive process of using knowledge to evaluate the truth value of a proposition. reasoning study investigation is the process of carrying out a plan or procedure so as to discover facts or information about the object of study. investigation predicting is the process of formulating a proposition about a state of affairs which might be realized in the future. predicting A database is a set of tables. database A quality that has a value that is decreased compared to normal or average. PATO:0002301 decreased A row represents a single, implicitly structured data item in a table. row A column is a vertical sequence of cells in a cellular automata. column 0 A database table is a set of named columns with zero or more rows composed of cells that contain column values and is part of a database. database table The minimal unit of a cellular automaton that can change state and has an associated behavior. cell (informational) database record A database entry is a single, implicitly structured data item in a table. database entry A database collumn is a column in a database table. database column disordered is a structural quality in which the parts of an object are non-rigid. disordered A unique cell is a cell that contains a unique value in the cellular automaton. unique cell A referenceing cell is a cell of a cellular automata that refers to another cell. referencing cell A referent cell is a cell that is the referent of some function or pointer. referent cell A database key is an informational entity whose value is constructed from one or more database columns. database key A primary database key is a database key that identifies every row of a table. primary database key null A foreign database key is a database key that refers to a key in some table. foreign database key p-value A p-value or probability value is the probability of obtaining a test statistic at least as extreme as the one that was actually observed, assuming that the null hypothesis is true probability value 0.0 1.0 A street name is the token given to identify a particular street. street name A postal code is a geographic coordinate composed of a series of letters and/or digits appended to a postal address for the purpose of sorting mail. postal code An apartment number is the number assigned to identify an apartment in a building of apartments. apartment number The uncertainty value (margin of error) of a measurement is a range of values likely to enclose the true value. uncertainty value A standard deviation (represented by the symbol σ) is the quantity of variation from the average (mean, or expected value). standard deviation A versioned record is a record for which there exists another variant based that was derived via modification of the facts. versioned record An object is an entity that is wholly identifiable at any instant of time during which it exists. core object to be a member of is the capability to be considered a part of a collection. to be a member of to distort is the capability to change the appearance of an entity by some transformation. to distort A primer is a nucleic acid that enables the synthesis of a complement strand of DNA by binding to it and acting as a point of transcription initiation. primer to bind to is the capability to physically interact with another object through a set of non-covalent interactions. to bind to A spatial boundary is the closure minus the interior of a subset of a topological space. spatial boundary hermaphrodite is a biological sex of an individual with both male and female sexual organs. PATO:0001827 hermaphrodite An answer is a reply to a question. answer A verbal language entity is a language entity that is manifested through sound. verbal language entity A page number is the count of a page in a sequence of pages. page number A linear position is the position of some object against a linear positioning system. linear position A sequence element position is the position of an element of a linear sequence. sequence element position ncRNA gene A non-protein coding RNA (ncRNA) gene is a gene that encodes for a RNA transcript that is not further translated into a protein product. http://purl.obolibrary.org/obo/SO_0001263 non-protein coding RNA (ncRNA) gene A sequence start position is the start position for a sequence of characters. sequence start position A sequence end position is the position of the last character in a sequence of characters relative to some linear frame of reference. sequence end position The number of elements of a finite set of objects. count A chemical role is a processual role held by a chemical entity. chemical entity role The role of a chemical participant that serves to increase the rate of reaction by lowering the activiation energy. catalytic role The role of a chemical entity that is modified in a chemical reaction. substrate role The role of a chemical entity present at the end of a chemical reaction. product role The role of a chemical entity involved in the mechanism for enzyme-mediated catalysis. cofactor role A co-factor role in which the chemical entity is modified during catalysis and must be regenerated. co-enzyme role A coenzyme role of a chemical entity that is covalently bonded to the enzyme. prosthetic group role A co-enzyme role of a chemical entity that is transiently associated, and is regenerated in a separate reaction. co-substrate role The role of a chemical entity that reduces the rate of reaction. inhibitor role The role of a chemical entity that increases the rate of reaction. activator role The quality of having a charge. charged The quality of not having a charge. uncharged A partial negative charge is a negative charge where the value of the charge is negative. partial positive charge A partial positive charge is a partial charge where the value of the charge is positive. partial negative charge The quality of having a charge that is not a full multiple of 1 unit charge. partial charge A complete charge is a charge where the value of the charge is a multiple of 1. complete charge Uniform Resource Locator A Uniform Resource Locator or Universal Resource Locator (URL) is a specific character string that constitutes a reference to an Internet resource. URL affection is an emotion characterized with a feeling or type of love for another living thing. affection angst is the intense feeling of apprehension, anxiety or inner turmoil. angst Annoyance is an unpleasant emtion that is characterized by a abnormal or excessive sensitivity to some external stimulus. annoyance anxiety is an emotion charactersized by intense feeling of fear and concern coupled with a physical response. anxiety apathy is an emotion characterized by lack of interest, enthusiasm, or concern. apathy arousal is an emotion characterized by state of reactive to stimuli. It involves the activation of the reticular activating system in the brain stem, the autonomic nervous system and the endocrine system, leading to increased heart rate and blood pressure and a condition of sensory alertness, mobility and readiness to respond. arousal awe is an emotion produced by that which is grand, sublime or powerful and is characterized by a combination of joy, fear and admiration/reverence/respect. awe boldness is the trait of being willing to undertake things that involve risk or danger. boldness boredom is the emotion experience by those not interested in their surroundings or available activities. boredom contempt is disgust towards a lower status individual. contempt contentment is an emotion characterized by acknowledgement and satisfaction of the current state of affairs. contentment curiosity is the strong desire to know or learn something. curiosity depressed depression is an unpleasant emotion linked to aversion to activity that can affect a person's thoughts, behavior, feelings and physical well-being. Depressed individuals may feel sad, anxious, empty, hopeless, worried, helpless, worthless, guilty, irritable, or restless. depression desire is a strong emotion of wanting to have something or wishing for something to happen. desire despair is depression, hopelessness or lack of hope. despair disappointed disappointing disappointment is the feeling of dissatisfaction that follows the failure of expectations or hopes to manifest. disappointment Disgust is a feeling of revulsion or profound disapproval aroused by something unpleasant or offensive. disgust dread is the instense negative emotion that induces fear and apprehension. dread ecstacy is an emotion characterized by a heightened state of consciousness with total involvement of a subject. ecstasy A positive emotion is an emotion that feels good. positive emotion negative emotion is an emotion that does not feel good. negative emotion Embarrassment is the emotion of intense discomfort with oneself, experienced upon having a socially unacceptable act or condition witnessed by or revealed to other. embarassment envy is an emotion that occurs when a person lacks another's (perceived) superior quality, achievement or possession and wishes that the other lacked it. envy euphoria is an emotion characterized by intense feelings of well-being, elation, happiness, ecstasy, excitement, and joy. euphoria excitement is a positive emotion of feeling great enthusiasm and eagerness. excitement Fear is a negative emotion induced by a perceived threat that induces one to hide or move quickly away from the location of the perceived threat. fear Frustration is an emotion that arises from the perceived resistance to the fulfillment of individual will. frustration appreciation gratefulness gratification thankfullness Gratitude, thankfulness, gratefulness, or appreciation is a feeling, emotion or attitude in acknowledgment of a benefit that one has received or will receive. gratitude happiness is an emotion characterized by positive or pleasant emotions ranging from contentment to intense joy. happiness guilty Guilt is the emotion borne from feeling responsible for the commission of an offense and arises out of public humiliation. guilt grief is an emotion in response to loss, whether physical or abstract including death, unemployment, ill health or the end of a relationship. grief hope is an emotion of belief in a positive outcome related to events and circumstances in one's life. hope Hostility is the intense negative emotion of being in conflict or opposition to someone or something. hostility hurt is an unpleasant feeling, emotion or sensation. hurt Hysteria is an unmanageable emotion. hysteria indifference is an emotion characterized by lack of interest, concern, or sympathy. indifference interest is the emotion of wanting to know or learn about something or someone. interest jealousy is an emotion and typically refers to the negative thoughts and feelings of insecurity, fear, and anxiety over an anticipated loss of something that the person values, particularly in reference to a human connection. jealousy joy is an emotion of intense happiness. joy loathing is an intense dislike or disgust. loathing Loneliness is an unpleasant emotion in which a person feels a strong sense of emptiness, yearning distress and solitude resulting from inadequate quantity or quality of social relationships. loneliness lust is the strong desire for sex. lust misery is a feeling of great unhappiness, suffering and/or pain. misery Panic is a sudden emotion of fear which is so strong as to dominate or prevent reason and logical thinking, replacing it with overwhelming feelings of anxiety and frantic agitation consistent with an animalistic fight-or-flight reaction. panic passion is the intense desire for something. passion Pity is the emotion of sadness or sorrow for another. pity pleasure is an emotion of happy satisfaction and enjoyment. pleasure pride is an emotion of satisfaction of attachment toward one's own or another's choices and actions, or toward a whole group of people, and is a product of praise, independent self-reflection, or a fulfilled feeling of belonging. pride Rage is a feeling of intense anger that is associated with the Fight-or-flight response. rage regret is a feeling of sadness, repentance, or disappointment over something that has happened or been done. regret remorse is an emotion of personal regret felt by a person after he or she has committed an act which they deem to be shameful, hurtful, or violent. remorse sad unhappiness unhappy sadness is emotional pain associated with, or characterized by feelings of disadvantage, loss, despair, helplessness, sorrow, and rage. sadness satisfaction is an emotion of fulfillment of one's wishes, expectations, or needs, or the pleasure derived from this. satisfaction is the emotion of fulfillling one's wishes, expectations, or needs. satisfaction satisfaction contentment pleasure shame is the emotion borne from feeling responsible for the commission of an offense. shame shock is an emotion of sudden upset or surprise. shock shyness is an emotion of apprehension, lack of comfort, or awkwardness experienced when in proximity to, approaching, or being approached by other individuals, especially in new situations or with unfamiliar individuals. shyness sorrow is the emotion that is characterized by a long term state of intense sadness, distress and a degree of resignation (not accepting). sorrow Suffering is the unpleasant emotion and aversion associated with the perception of harm or threat of harm in an individual. suffering surprise is a brief emotion experienced as the result of an unexpected event. surprise terror is the extreme feeling of fear. terror wonder is an emotion of perceiving something very rare or unexpected, but not threatening. wonder worry is the emotion characterized by concer over a real or imaginary issue. worry A department chain role is the role of an individual that heads a department at a academic organization. department chair role A student advisor role is the role of an individual employed at an academic organization that is involved in advising students. student advisor role An undergraduate student advisor role is the role of an individual employed at an academic organization that is involved in advising undergraduate students. undergraduate student advisor role A graduate student advisor role is the role of an individual employed at an academic organization that is involved in advising graduate students. graduate student advisor role The role of a chemical entity present at the beginning of a chemical reaction. reactant role The role of a chemical entity that modifies the rate of reaction. regulator role An investigational role is a role held by participants involved in an investigation. investigational role The role of an organism in providing resources to maintain the survival and/or reproduction of another organism. host role A subject role is the role of an individual that is the target of the study. subject role A publishing role is the role of an individual that is involved in the preparation and issue of creative works for consumption by a wider audience. publishing role A publisher role is the role of an individual that prepares and issues creative works. publisher role An author role is the role of an individual that creates a creative, written work. author role A buffer role is the role of a chemical substance which maintains a pH at a near constant value. buffer role A chemical substance role is a chemical entity role held by a chemical substance. chemical substance role A molecular entity role is a chemical entity role held by a molecule. molecular entity role A toxin role is a toxic role of a chemical substance that is poisonous and is produced by an organism. toxin role A toxic role is the role of a chemical substance that is poisonous. toxic role A role of a chemical substance that participates in a chemical reaction as part of some scientific investigation. reagent role to luminesce is to emit light through cold body radiation to luminesce to fluoresce is to emit light as a result of absorbing light or other electromagnetic radiation. to fluoresce A molecular tracer role is a reactant role of a molecular entity that serves as a marker for the presence, abundance, or location of a molecular target that it associates with. molecular tracer role An association is a relationship between two or more entities derived by some informational analysis. association 2 A statistical association is any relationship between two measured quantities that renders them statistically dependent. statistical association A chromosome is a molecular complex of circular or linear DNA and bound proteins. chromosome A top value axis is a value axis that is spatially positioned to the top of the plot area. top value axis A bottom value axis is a value axis that is spatially positioned to the bottom of the plot area. bottom value axis A chart is a figure that displays the relationship among tabular numeric data, functions or some kinds of qualitative structures. chart A map is a a visual representation of an area that depicts the relationship between elements of that space. map A heatmap is a graphical representation of data where the individual values contained in a matrix are represented as colors. heatmap A streamgraph is a multi-line stacked graph that yields the appearance of continuous y-values across the x-axis. streamgraph A boxplot (box-and-whisker diagram) is a convenient way of graphically depicting groups of numerical data through their five-number summaries: the smallest observation (sample minimum), lower quartile (Q1), median (Q2), upper quartile (Q3), and largest observation (sample maximum). boxplot A geographic heatmap is a graphical representation of data over a geographic region where individual values are represented as colors. geographic heatmap A histogram is a graphical representation of data which consists of tabular frequencies, shown as adjacent rectangles, over discrete intervals (bins) , with an area equal to the frequency of the observations in the interval. histogram A measurement scale is a functional specification that specifies an allowed range of categories or values. measurement scale A nominal scale of measurement only specifies a limited set of categories. nomimal scale A binary scale is a measurement scale that specifies a choice between two values. binary scale A numeric scale of measurement is one that only specifies numeric values. numeric scale A decimal scale of measurement is one that only specifies decimal values. decimal scale An integer scale of measurement is one that only specifies integer values. integer scale modification modifying is the process by which an entity gains or loses parts, qualities, roles, dispositions, functions, etc, but maintains their identity through these changes. modifying reproducing is a process characterized by creation of an entity that is similar or exactly the same as the template from which it is derived. reproducing An independent variable is a variable that may take on different values independent of other elements in a system. independent variable A dependent variable is one whose value changes as a consequence of changes in other values in the system. dependent variable A Gantt chart is a bar chart that illustrates a project schedule. Gantt chart A correlation is a statistical relationship involving dependence between two random variables or datasets. correlation A television program is a audiovisual media that is produced and broadcast using a television. television program A radio receiver is a communication device that receives its input from an antenna, uses electronic filters to separate a wanted radio signal from all other signals picked up by this antenna, amplifies it to a level suitable for further processing, and finally converts through demodulation and decoding the signal into a form usable for the consumer, such as sound, pictures, digital data, measurement values, navigational positions. radio receiver The telephone is a communications device that transmits and receives sounds, and are minimally composed of a microphone to speak into, a speaker'which reproduces the voice of the other person and a ringer which makes a sound to alert the owner when a call is coming in. telephone A radar is an object-detection system which uses radio waves to determine the range, altitude, direction, or speed of objects. radar A pie chart is a circular chart divided into sectors each of whose length is proportional to the quantity it represents. pie chart A matrix chart summarizes a multidimensional data set in a grid. matrix chart A network diagram consists of a set of vertices connected by edges. network diagram A block histogram contains an x-axis that is divided into bins which correspond to value ranges. Each item in the data set is drawn as a rectangular block, and the blocks are piled into the bins to show how many values in each range. block histogram A bubble chart contains circles whose area corresponds to a value. bubble chart A stack graph is a statistical graph which presents multiple series in which the distance between one series and another indicates the relative contribution to the total for any x-value. stack graph A treemap is a chart that fully partitions the area into a set of rectangles whose area represents its relative value. treemap A word tree is a chart that links phrases with contexts through a tree-like branching structure. word tree A textual chart is a chart containing text. textual chart word cloud A tag cloud is a visualization of word frequencies. tag cloud A phrase net diagram illustrates the relationship between different words used in a text. phrase net diagram A mereological chart is a chart that illustrates the parts in the context of the whole. mereological chart conversing a form of interactive, spontaneous communication between two or more agents who are following rules of etiquette. conversing A numeric label is a number used as a label. numeric label A start position is the proximal position of an object relative to an origin in a linear system. start position An interval is a set of real numbers that includes all numbers between any two numbers in the set. an interval is a set of real numbers with the property that any number that lies between two numbers in the set is also included in the set. interval interval The set of all numbers x satisfying 0<=x<=1 is an interval which contains 0 and 1, as well as numbers between them. A tree diagram is a hierarchical network diagram in which a root vertex is connected to one or more other vertices through a directed edge, which in turn may be connected to other vertices. tree diagram A flowchart is a diagram that represents an algorithm or process, showing the steps as boxes of various kinds, and their order by connecting these with arrows. flowchart A Venn diagram is a chart that illustrates all possible logical relations between a finite collection of sets as overlapping circles. venn diagram A dendrogram is a tree diagram used to illustrate the arrangement of the clusters produced by hierarchical clustering. dendrogram apprehension is the negative emotion that something unpleasant will occur. apprehension resentment is disgust directed toward a higher status individual. resentment Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. pain A default parameter is a parameter which has a default value. default parameter stop position An end position is the distal position of an object relative to an origin in a linear system. end position sick is the status of a living organism that is behaving at a sub-optimal level. sick An environment is a geographic region that hosts certain processes or objects. environment A device is usually a constructed tool. device A communication device is a device that facilitates the transmission of information through encoded in an audio or digital signal between a sender and a receiver. communication device existence quality is the quality of an entity that describe in what environment it is known to exist. existence quality real is the quality of an entity that exists in real space and time. real fictional is the quality of an entity that exists only in a creative work of fiction. fictional virtual is the quality of an entity that exists only in a virtual setting such as a simulation or game environment. virtual not started is the status of a process that is predicted to exist but has not yet begun. not started A standard operating procedure is a specification approved for use in specific environments. standard operating procedure agreement quality is a quality that exhibits the degree of consensus for some set of assertions. agreement quality agreement is the result of consensus decision making when members of the group agree. agreement agreement is the result of consensus decision making when members of the group do not all agree. disagreement A poison role is the role of a substance that causes some negative disturbance in an organism. poison role communication communicating is the process of conveying information through the exchange of thoughts, messages, or information, as by speech, visuals, signals, writing, or behaviour. communicating observational study draws inferences about the possible effect of a treatment on subjects, where the assignment of subjects into a treated group versus a control group is outside the control of the investigator observational study A syllable is a verbal entity of language having one vowel sound, with or without surrounding consonants, forming the whole or a part of a word. syllable A consonant is a verbal entity of language that is articulated with complete or partial closure of the vocal tract. consonant A vowel is a verbal entity of language that is pronounced with an open vocal tract so that there is no build-up of air pressure at any point above the glottis. vowel A sign language (also signed language) is a language that involves manual communication and body language to convey meaning. This can involve simultaneously combining hand shapes, orientation and movement of the hands, arms or body, and facial expressions to fluidly express a speaker's thoughts. sign language A verbal language is a language that uses sounds to communicate. verbal language written language is a language that is communicated through a writing system. written language A gene-disease association is an association between a gene and a disease. gene-disease association A genome is a collection of nucleic acids. genome A gene that contains an open reading frame which codes for a protein. http://purl.obolibrary.org/obo/SO_0001217 protein coding gene A gene that codes for a functional RNA molecule. functional rna coding gene A predicted gene is a gene that was identified through computational method but has not been experimentally validated. predicted gene A pseudo gene is a region of a nucleic acid that either cannot be transcribed, or its RNA transcript cannot be translated. http://purl.obolibrary.org/obo/SO_0000336 pseudogene A sequence assembly is a sequence that is produced as by the alignment of two or more sequences. sequence assembly An experimentally validated gene is a gene whose existence has been demonstrated through experimental methods. validated gene unsupported is an existence quality in which there is no evidence to support the existence of the entity in any world (real or hypothetical) unsupported A chemical-disease association is an association between a chemical and a disease. chemical-disease association study An experiment is an investigation that has the goal of verifying, falsifying, or establishing the validity of a hypothesis. experiment suspended is the status of a process that is no longer progressing towards completion. suspended cancelled is a process status in which the process, while planned to occur, will not occur. cancelled aborted is a process status in which a started process will not complete as intended. aborted literature curation is the process of an agent selecting and extracting terms and phrases from a document. literature curation A procedure is a process that attempts to achieve one or more objectives by following an established set of actions. procedure A clinical trial is an intervention trial to determine the safety and efficacy of medical interventions (e.g., drugs, diagnostics, devices, therapy protocols). clinical trial A medical diagnosis (often simply termed diagnosis) refers to the process of attempting to determine or identify a possible disease or disorder. medical diagnosis A differential diagnosis (sometimes abbreviated DDx, ddx, DD, D/Dx, or ΔΔ) is a systematic diagnostic method used to identify the presence of an entity where multiple alternatives are possible (and the process may be termed differential diagnostic procedure), and may also refer to any of the included candidate alternatives (which may also be termed candidate condition). differential diagnosis A diagnostic opinion is an opinion resulting from a medical diagnostic procedure. diagnostic opinion An opinion is a belief that is the result of emotion or interpretation of facts. opinion A chemical effect is a chemical interaction in which a chemical elicits a marked characteristic of a biological system. chemical effect A drug-drug interaction is an interaction in which two drugs interact in such a way to produce a non-additive biological response. drug drug interaction 2 bioassay An assay is an investigative (analytic) procedure in laboratory medicine, pharmacology, environmental biology, and molecular biology for qualitatively assessing or quantitatively measuring the presence or amount or the functional activity of a target entity (the analyte) which can be a drug or biochemical substance or a cell in an organism or organic sample. assay toxicity is the quality of a chemical substance to cause injury to an organism in a dose dependent manner. toxicity toxic is the quality of a substance imparing the normal functioning of a system. toxic non toxic is the quality of a substance having no damaging effect to a system. non toxic chemical quality is the quality of a chemical entity. chemical quality healthy is an organismal state of complete physical, mental and social well-being. healthy age is the length of time that a person has lived or a thing has existed. age ethnicity is the biological quality of membership in a social group based on a common heritage. ethnicity race is a characteristic of an individual by heritable phenotypic characteristics, geographic ancestry, physical appearance, ethnicity, and social status. race An ethnic group is a group of people whose members identify with each other through a common heritage, consisting of a common culture, including a shared language or dialect. ethnic group A syndrome is composed of a set of several clinically recognizable features, signs (observed by someone other than the patient), symptoms (reported by the patient), phenomena or characteristics that often occur together. syndrome A ratio is a relationship between two numbers of the same kind expressed arithmetically as a dimensionless quotient of the two which explicitly indicates how many times the first number contains the second. ratio A dose is the quantity of a chemical substance administered to a biological system. dose effective dose is the amount of a substance required to produce an effect on a predefined percentage of a population. effective dose An expected value (or e-value) is the weighted average of all possible values that a random variable can take on. expected value clinical laboratory test A diagnostic test is a procedure performed to confirm, or determine the presence of disease in an individual suspected of having the disease, usually following the report of symptoms, or based on the results of other medical tests. diagnostic test A medical screening is a medical test or series used to detect or predict the presence of disease in individuals at risk for disease within a defined group, such as a population, family, or workforce medical screening A medical procedure is a procedure to identify, examine, alleviate or eliminate an undesirable biological disease or disorder. medical procedure A prognosis is a proposition about the likely course of a disease, the chance of recovery or recurrence. prognosis A report is a textual document made that present focused, salient content to a specific audience. report A medical health record is a record of a single patient's medical history. medical health record A medical report is a report prepared by a health care practioner about test outcomes or health status of an individual. medical report A peer reviewed article is an article that has undergone peer-review and deemed acceptable for publication. peer reviewed article A major version number is a version of a software that exhibits a significant change in functionalilty from a prior version. major version number A minor version number is a version of a software that exhibits minor features or significant fix from a prior version. minor version number A revision number is a version of a software in which bugs have been fixed from a prior version. revision number text quality is the quality of a textual entity. text quality reviewed is the quality of a textual entity that has been examined and commented on by another party. reviewed peer-reviewed is the quality of a textual entity that has been examined and commented by a peer expert reviewer. peer-reviewed drafted draft is the quality of text that has not yet complete. draft finalized is the quality of a textual entity that is in its final form. finalized editor reviewed is the quality of a textual entity that has been examined and commented on by an editor. editor reviewed written is the quality of information that is embodied as visual glyphs in some material form. written A morpheme is the smallest semantically meaningful unit in a language. morpheme study protocol A study design is a protocol for the proper execution of a study which normally requires a carefullly crafted research question or hypothesis and at least one variable under observation and observed values for that variable. study design A recipe is a set of instructions that describe how to prepare or make something. recipe An experimental protocol is an action specification with respect to the design and implementation of experiments. In addition to providing a detailed set of procedures and lists of required equipment and instruments, experimental protocols often include information on safety precautions, the calculation of results and reporting standards, including statistical analysis and rules for predefining and documenting excluded data to avoid bias. experimental protocol A viroid is a molecule of RNA that does not code for and is not protected by a protein coat. viroid The quality of being polar or not polar. polar quality polar is the quality of having a dipole. polar non-polar is the quality of not having a dipole. non-polar An intervention study has the objective of improving the condition of an individual or a group of individuals, and demonstrates the magnitude of that capability by comparing it to a control group. intervention study sampling is the act of obtaining a sample, whether through selection, collection or preparation. sampling A sample is a limited quantity of something (e.g. an individual or set of individuals from a population, or a portion of a substance) to be used for testing, analysis, inspection, investigation, demonstration, or trial use. sample data analysis is a process of inspecting, cleaning, transforming, and modeling data with the goal of highlighting useful information, suggesting conclusions, and supporting decision making. data analysis data collection is the process of acquiring information. data collection A reason is a justification that specifies the motive for an action or a determination. reason measurement measuring is the process of determining the size, amount, or degree of (something) by using an instrument or device marked in standard units measuring observation observing is a process of passive interaction in which one entity makes note of attributes of one or more entities. observing character offset The ordinal position of a character in a sequence of characters. character position The position of the first character in a word as an offset from the first character of the text in which it is found. word start position word end position is the position of the last character in a word as an offset from the first character of the text in which it is found. word end position gesturing is a form of non-verbal communication in which visible bodily actions communicate particular messages, either in place of speech or together and in parallel with spoken words. Gestures include movement of the hands, face, or other parts of the body. gesturing planned is a process status for a process that has not yet started, but is referred to in a plan. planned A population is all the organisms that both belong to the same group or species and live in the same geographical area. population A human population refers to a collection of human beings. human population A group of people affiliated by consanguinity, affinity, or co-residence. family A community is a sizeable social unit that shares common values. community speculation is an opinion based on incomplete evidence. speculation A study is a process that realizes the steps of a study design. study In a controlled observational cohort study, two groups of subjects are selected from two populations that are thought to differ in only one characteristic. The groups of subjects are studied for a specific period and contrasted at the end of the study period. controlled observational cohort study A control group is a group of individuals that are not subject to an intervention of interest, but rather serve as a baseline to compare the outcomes in the intervention group. control group An intervention group is a group of individuals that are subject to an intervention. intervention group controlled variable extraneous variable A control variable that is believed to alter the dependent or independent variables, but may not actually be the focus of the experiment. So that variable will be kept constant or monitored to try to minimise its effect on the experiment. control variable text span start position is the position (offset) of the first character of a text span in relation the text it is from. text span start position text span end position is the position (offset) of the last character of a text span in relation the text it is from. text span end position selector A text span is a subset of contiguous sequence of characters of a textual entity. text span A t-statistic is a ratio of the departure of an estimated parameter from its notional value and its standard error. t-statistic A microarray probe set identifier is an identifier for a set of probe pairs selected to represent expressed sequences on an array. microarray probe set identifier A microarray experiment is an experiment that involves a microarray device to measure the expression of one or more genes. microarray experiment A gene expression value is a measured value obtained from a gene expression experiment. gene expression value A differential gene expression ratio is the ratio of gene expression values from a test sample compared to a control sample. differential gene expression ratio A genotype is a functional specification of a biological entity in terms of its genetic composition (or lack thereof). genotype A vocabulary is a collection of terms. vocabulary A t-statistic based increased differential gene expression is a differential gene expression ratio in which the t-statistic is greater than zero. t-statistic based increased differential gene expression 0.0 A t-statistic based decreased differential gene expression is a differential gene expression ratio in which the t-statistic is less than zero. t-statistic based decreased differential gene expression 0.0 A date of database submission refers to the moment in time in which some information was submitted/received to a database system. date of database submission A liquid solution is a heterogeneous substance in a liquid state. liquid solution to remove a covalent bond is the capability to covalently modify a chemical entity by removing a covalent bond. to remove a covalent bond to add a covalent bond is the capability to covalently modify a chemical entity by adding a covalent bond. to add a covalent bond to modify electronically is the capability to change the electronic properties of an object. to modify electronically concentration is the amount of substance per unit volume of a solution concentration pH is a measure of the activity of the (solvated) hydrogen ion. pH is defined as the decimal logarithm of the reciprocal of the hydrogen ion activity, aH+, in a solution. pH homogeneous is a quality that describes the uniform composition of an object. homogeneous homogeneous is a quality that describes the varied composition of an object. heterogeneous A structural quality is a quality of an object that describes its structure. structural quality rigid is the quality of maintaining structural integrity (and not bending) under pressure. rigid bent is the quality of a line being sharply curved or having an angle. bent curved is the quality of a line that deviates from straightness in a smooth, continuous fashion. curved electronic configuration electronic structure is the electron configuration is the distribution of electrons of an atom or molecule (or other physical structure) in atomic or molecular orbitals. electronic structure the electron configuration of the neon atom is 1s2 2s2 2p6. A crystal structure is the arrangement of atoms or molecules in a crystalline liquid or solid. crystal structure to interact and to be interacted with is a mutual disposition of interacting objects. to interact and to be interacted with to gain a covalent bond is the capability of a chemical entity to have bonds added. to gain a covalent bond to lose a covalent bond is the capability of a chemical entity to have bonds removed. to lose a covalent bond to ingest is the capability to take into the body by the mouth for digestion or absorption. to ingest to produce is the capability to create new objects to produce biological pathway A pathway is an effective specification that outlines a set of actions that forms a way to achieve an objective. pathway A central tendency measure is a central value or a typical value for a probability distribution. centrality measure arithmeritic mean average A mean is the central tendency of a collection of numbers taken as the sum of the numbers divided by the size of the collection. mean A median is the numerical value separating the higher half of a sample, a population, or a probability distribution, from the lower half. median A mode is the value that appears most often in a set of data. mode A sum is the result of adding a set of values together. sum min A minimal value is smallest value of an attribute for the entities in the defined set. minimal value max A maximal value is largest value of an attribute for the entities in the defined set. maximal value A count of the instances of a class or members in a collection. member count A union is a list of all of the values of an attribute for the entities in the defined set. union An intersection is a list of only the values of an attribute for the entities in the defined set where all entities have that value. intersection ordered list A sequence is an ordered list of entities. Like a set, it contains members (also called elements, or terms). sequence For example, (M, A, R, Y) is a sequence of letters that differs from (A, R, M, Y), as the ordering matters, and (1, 1, 2, 3, 5, 8), which contains the number 1 at two different positions, is a valid sequence. A gene-variant disease association in which a mutation in the gene/protein results in the development or maintenance of the disease. gene-disease association linked with causal mutation gene-disease association arising from a therapeutic role of the gene/protein A gene disease association in which the gene is a therapeutic marker for the disease. therapeutic gene-disease association A gene-disease association in which the gene/protein is involved in the etiology or maintenance of the disease. gene-disease biomarker association gene variant-disease association A gene-disease association in which a sequence variation (a mutation, a SNP) is associated with the disease. gene-disease association linked with genetic variation A gene-disease association in which the disease phenotype is associated with an altered expression of the gene. gene-disease association linked with altered gene expression A gene-disease association in which the disease phenotype is associated with post-translational modifications in the protein product. gene-disease association linked with post-translational modification methylation or phosphorylation of protein product A process that modulates the frequency, rate or extent of transcription. regulation of transcription A process that modulates the frequency, rate or extent of translation. regulation of translation A process that modulates the frequency, rate or extent of process involved in the creation or destruction of a molecule. regulation of molecular quantity A process that modulates the frequency, rate or extent of process involved in the production of a molecule. regulation of molecular production A process that modulates the frequency, rate or extent of process involved in the destruction of a molecule. regulation of molecular degradation A process mediated by a protein that modulates the frequency, rate or extent of translation. protein mediated regulation of translation A process mediated by rna that modulates the frequency, rate or extent of translation. rna mediated regulation of translation The process of maintaining some the frequency, rate or extent of another process. process maintenance The increase of regulation leads to a increased occurence of processes of the target type. increased frequency of process from increased regulation The increase of regulation leads to a decreased occurence of processes of the target process type. decreased frequency of process from increased regulation regulation of a process duration is a process that modulates the frequency of another process relative to some reference process. regulation of process frequency regulation of a process duration is a process that modulates the duration of another process relative to some reference process. regulation of process duration increased duration of process from increased regulation is a process in which the duration of the target process is increased as a result of increased regulation. increased duration of process from increased regulation decreased duration of process from increased regulation is a process in which the duration of the target process is decreased as a result of increased regulation. decreased duration of process from increased regulation regulation of a process spatial extent is a process that modulates the spatial extent of another process relative to some reference process. regulation of process spatial extent heating the solution causes greater diffusion of a chemical. The increase of regulation leads to a increased spatial extent of the target process. increased spatial extent of process from increased regulation The increase of regulation leads to a decreased spatial extent of the target process. decreased spatial extent of process from decreased regulation maintenance of spatial extent of process is a regulation of a process' spatial extent within some specified parameter. maintenance of spatial extent of process maintenance of duration of process is a process that regulates a target process to maintain its duration within an expected interval. maintenance of duration of process maintenance of frequency of process is a process that regulates the number of occurences of a target process type to a specified number or interval. maintenance of frequency of process regulation of a participant quantity is the regulation of a process in which the quantity of its partcipants is changed. regulation of object quantity increased regulation leads to an increase in the number of target objects of a specified type. increased object production from increased regulation increased regulation leads to a decrease in the number of target objects of a specified type. decreased object production from increased regulation increased regulation leads to an increase in the consumption of an object of specified type. increased object consumption from increased regulation increased regulation leads to an decrease in the consumption of an object of specified type. decreased object consumption from increased regulation A process that modulates the frequency, rate or extent of process involved in the consumption of an object. regulation of object consumption regulation of a participant quantity is the regulation of a process in which the quantity of a selected participant is increased. regulation of object production maintenance of quantity of object production is a regulation of object production in which the number of objects produced is held more or less constant. maintenance of quantity of object production regulation of a participant quantity is the regulation of a process in which the quantity of a selected participant is maintained at a steady level. maintenance of level of object consumption number of objects produced is a count of objects that were produced in some process. number of objects produced number of objects consumed is a count of objects that were consumed in some process. number of objects consumed A difference in number of objects produced is a count of the number of objects produced with respect to a second variable (space, time, etc) difference in number of objects produced An increase in the number of objects produced is the positive value of a difference in number of objects produced. increase in number of objects produced An decrease in the number of objects produced is the negative value of a difference in number of objects produced. decrease in number of objects produced user account allows a user to authenticate to system services and be granted authorization to access them. user account An annotation is a written explanatory or critical description, or other in-context information (e.g., pattern, motif, link), that has been associated with data or other types of information. annotation A comment is a verbal or written remark often related to an added piece of information, or an observation or statement. comment An audio recording is an electrical or mechanical inscription and re-creation of sound waves, such as spoken voice, singing, instrumental music, or sound effects. audio recording An issue is a single instance of a periodically published journal, magazine, or newspaper. issue A slideshow is a visual presentation of information contained within a collection of slides. slideshow dbxref A database cross-reference is an association between one data item and another. database cross-reference An exact cross-reference is a database cross-reference in which one entity is equivalent to the other based on all the entitie's attributes (minus the source). exact cross-reference double stranded nucleic acid is a molecular complex composed of two weakly connected deoxyribonucleic acids. double stranded DNA 2 A nucleic acid strand is a single-stranded nucleic acid that is part of a double stranded nucleic acid complex. nucleic acid strand forward strand The positive nucleic acid strand refers to the strand that is to be read 5' to 3'. positive nucleic acid strand reverse strand The negative nucleic acid strand is the strand that is that is complimentary to the forward strand and appears from 3' to 5'. negative nucleic acid strand double stranded nucleic acid is a molecular complex composed of two weakly connected nucleic acids. double stranded nucleic acid 2 double stranded nucleic acid is a molecular complex composed of two weakly connected ribonucleic acids. double stranded RNA 2 full agreement is the result of consensus decision making when members of the group unanimously agree. full agreement A mass spectrometry experiment is an experiment that involves the use of a mass spectrometer. mass spectrometry experiment full agreement is the result of consensus decision making when members of the group unanimously disagree. full disagreement rRNA gene A ribosomal RNA gene is a gene that codes for a ribosomal RNA molecule. http://purl.obolibrary.org/obo/SO_0001637 ribosomal RNA gene A statement is a proposition that is either (a) a meaningful declarative sentence that is either true or false, or (b) that which a true or false declarative sentence asserts. statement A slope or gradient of a line describes its steepness, incline, or grade. A higher slope value indicates a steeper incline. Slope is normally described by the ratio of the "rise" divided by the "run" between two points on a line. slope A software process identifier is an identifier for a software process in some operating system. software process identifier hypothetical is the quality of an entity that is conjectured to exist. hypothetical A database row is a row that is part of a database table. database row a SADI semantic web service is a semantic web service that follows the SADI specification sadi SADI semantic web service http://en.wikipedia.org/wiki/SADI a semantic web service is a web service that provides a formal, machine understanble description of its functionality. semantic web service a REST web service is a web service that provides functionality according to the Representational State Transfer (REST) specification. REST web service http://en.wikipedia.org/wiki/REST a SOAP web service is a web service that implements Simple Object Access Protocol (SOAP). SOAP web service http://en.wikipedia.org/wiki/SOAP A web service invocation involves the execution of a web service. web service invocation A SADI web service invocation is the excution of a SADI web service. sadi SADI web service invocation media are audo/visual/audiovisual modes of communicating information for mass consumption. media Behaviour is the set of actions and mannerisms made by systems (biological or otherwise) in response to stimuli or inputs, whether internal or external, conscious or subconscious, overt or covert, and voluntary or involuntary. behaviour+ core behaviour history is a sequence of past events. history A structural motif is a pattern in a structure formed by a spatial arrangement of objects (e.g. atoms). structural motif consensus is an acceptable resolution, one that can be supported, even if not the preferred outcome for each individual. consensus A process that increases the frequency, rate or extent of process involved in the destruction of a molecule as a result of increased regulation. increased molecular degradation from increased regulation A process that decreases the frequency, rate or extent of process involved in the destruction of a molecule as a result of decreased regulation. decreased molecular degradation from decreased regulation A process that increases the frequency, rate or extent of process involved in the destruction of a molecule as a result of decreased regulation. increased molecular degradation from decreased regulation A process that decreases the frequency, rate or extent of process involved in the destruction of a molecule as a result of increased regulation. decreased molecular degradation from increased regulation A process that increases the frequency, rate or extent of process involved in the production of a molecule as a result of increased regulation. increased molecular production from increased regulation A process that decreases the frequency, rate or extent of process involved in the production of a molecule as a result of increased regulation. decreased molecular production from increased regulation A process that increases the frequency, rate or extent of process involved in the production of a molecule as a result of decreased regulation. increased molecular production from decreased regulation A process that decreases the frequency, rate or extent of process involved in the production of a molecule as a result of decreased regulation. decreased molecular production from decreased regulation increased chemical destruction is a process in which there is an increase in the amount of chemical destroyed relative to some reference process increased chemical destruction decreased chemical destruction is a process in which there is a decrease in the amount of chemical destroyed relative to some reference process decreased chemical destruction An assertional qualifier is the quality of affirmation, either being positive or negative. assertional qualifier positive is an assertional qualifier that expresses the validity or truth of a basic assertion. positive negative is an assertional qualifier that expresses the falsity or lack of truth of a basic assertion. negative intensity is a quality that represents the strength or degree of something. intensity mild is a qualitative intensity value that is more intense than weak, but less intense than moderate. mild moderate is a qualitative intensity value that is more intense than mild, but less intense than strong. moderate severe is a qualitative intensity value that is more intense than strong, but less intense than fatal. severe fatal is a qualitative intensity value that is more intense than severe, leading to the death/non-functioning of a system. fatal strong is a qualitative intensity value that is more intense than moderate, but less intense than severe. strong weak is a qualitative intensity value that is more intense than none, but less intense than mild. weak to test a hypothesis is the capability to evaluate the truth value of a proposition based on gathered evidence. to test a hypothesis to characterize is the capability to classify the attributes or features of an entity against a reference classification. to characterize to describe is the capabilty to communicate facts about an entity. to describe The 5' splice site is the terminal region of an exon that is 5' to the intron that is to be excised. 5' splice site The 3' splice site is the terminal region of an exon that is 3' to the intron that is to be excised. 3' splice site An amino acid is an organic molecule composed of a carbon bonded to four different groups: a carboxyl group, an amino group, an R group, and a hydrogen atom. In the case of glycine, the R group is another hydrogen atom. amino acid A cisregulatory element is a DNA sequence located on the same DNA strand or chromosome as the gene whose expression it affects. cis regulatory element A trans-regulatory element is a DNA sequence associated with the regulation of a gene located outside the genomic region supporting the corresponding structural DNA region of the trans-regulatory element (i.e., a different DNA strand or different chromosome). trans-regulatory element A small cytoplasmic RNA (scRNA) gene is a gene that encodes a small (7S; 129 nucleotides) RNA molecule found in the cytosol and rough endoplasmic reticulum that are normally associated with proteins that are involved in specific selection and transport of other proteins. http://purl.obolibrary.org/obo/SO_0001266 small cytoplasmic RNA (scRNA) gene A small nuclear RNA (snRNA) gene is a gene that encodes a small niuclear RNA molecule. http://purl.obolibrary.org/obo/SO_0001268 small nuclear RNA (snRNA) gene A small nucleolar RNA (snoRNA) gene is a gene that encodes a small RNA that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. http://purl.obolibrary.org/obo/SO_0001267 small nucleolar RNA (snoRNA) gene solube RNA (sRNA) gene tRNA gene A transfer RNA (tRNA) gene is a gene that codes for a tRNA used in the translation of a messenger RNA (mRNA) to produce a protein product. http://purl.obolibrary.org/obo/SO_0001272 transfer RNA (tRNA) gene scRNA A small cytoplasmic RNA (scRNA) molecule is a small (7S; 129 nucleotides) RNA molecule found in the cytosol and rough endoplasmic reticulum that are normally associated with proteins that are involved in specific selection and transport of other proteins. small cytoplasmic RNA (scRNA) tRNA A transfer RNA (tRNA) is an RNA molecule that aids in the translation of a messenger RNA (mRNA) to produce a protein product. transfer RNA (tRNA) snRNA A small nuclear RNA (snRNA) is a small RNA molecule that is located in the nucleus of a cell. small nuclear RNA (snRNA) snoRNA A small nucleolar RNA (snoRNA) is a small RNA that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. small nucleolar RNA (snoRNA) A non-protein coding RNA (ncRNA) is a RNA molecular that cannot be used as a template for generating a protein product. non-protein coding RNA (ncRNA) A data collection device is a device that collects information about one or more objects. data collection device A mass spectrometer is a device that identifies ions based on their mass to charge ratio using an electromagnetic field. http://purl.obolibrary.org/obo/OBI_0000049 mass spectrometer microarray platform A microarray device is a device that identifies the binding of a target substance to a physically immobile substrate placed in an array or lattice. http://purl.obolibrary.org/obo/OBI_0000052 microarray device to identify is the capability to determine the identity of something. to identify nuclear magnetic resonance device A nuclear magnetic resonance (NMR) device is a device that applies a magnetic field to perturb nuclei with an odd number of protons and/or of neutrons in order to hav them absort and re-emit electromagnetic radiation. http://purl.obolibrary.org/obo/OBI_0000566 nmr device registry A catalog is a systemic collection of items of the same type. catalog Likelihood is the hypothetical probability that an event that has already occurred would yield a specific outcome. likelihood Log likelihood is the natural logarithm of the likelihood function log likelihood z-value, z-score, normal score, standardadized variable. A standard score is the (signed) number of standard deviations an observation or datum is above the mean. standard score an open interval is an interval that does not include its endpoints. open interval (0,1) is an open interval that is greater than 0 and less than 1. A closed interval is an interval that includes its endpoints, and is denoted with square brackets. closed interval [0,1] is a closed interval that is greater than or equal to 0 and less than or equal to 1. drug-pathway association a chemical-pathway association is an association between a chemical and a pathway. chemical-pathway association a left open interval is an interval in which there is no element that is smaller than all other elements. left open interval a right open interval is an interval in which there is no element that is greater than all other elements. right open interval a right closed interval is an interval in which there is a real number that is larger than all of its elements. right closed interval a left closed interval is an interval in which there is a real number that is smaller than all its elements. left closed interval a pharmacokinetic pathway is a metabolic pathway which describes the metabolism of a drug molecule. pharmacokinetic pathway a pharmacodynamic pathay is a regulatory pathway in which a drug molecule regulates the activity of one or more components organized in a pathway. pharmacodynamic pathway a chemical-gene association is an association between a chemical and a gene. chemical-gene association set item is an item in a set. set item a collection item is an item in a collection. collection item a list item is an item in a list. list item an ordered list item is an item in an ordered list. ordered list item an anatomical entity is an object that is a structural part (material or immaterial) of a biological entity. anatomical entity zygosity is the quality pertaining to the allelic complement of a biological system at a single locus on the DNA. zygosity homozygous is the quality of a biological organism in which there are two identical alleles at a given locus. homozygous homozygous is the quality of a biological organism in which there are two different alleles at a given locus. heterozygous hemizygous is the quality of a biological organism in which, based on the ploidy of the organism, there is half the number of alleles than normal at a given locus. hemizygous nullizygous is the quality of a biological organism in which there are no allelles at a given locus. nullizygous parental transmition is the quality of a biological organism in which the (genetic) material is transmitted from a parental unit. parental transmission maternally transmitted is the quality of a biological organism in which the (genetic) material is transmitted from the maternal line. maternally transmitted paternally transmitted is the quality of a biological organism in which the (genetic) material is transmitted from the paternal line. paternally transmitted helicity is the quality of being helical helicity a circularly helical quality is the quality of a helix that is connected in a circle or loop. circularly helical left-handed helical quality is the quality in which a clockwise screwing motion moves the helix towards the observed along the line of sight along the helix's axis. left-handed helical right-handed helical quality is the quality in which a clockwise screwing motion moves the helix away from the observed along the line of sight along the helix's axis. right-handed helical a coding frame offset is a numeric value that indicates the number of bases from a reference start codon position. coding frame offset a coding sequence is a sequence of nucleotides which encode a RNA or protein product.. coding sequence Humiliation is the abasement of pride, which creates mortification or leads to a state of being humbled or reduced to lowliness or submission. humiliation hunger is the craving for food. hunger discouraged Discouragement is the emtion of having lost confidence or enthusiasm. discouragement suicidal is the emotion of being deeply unhappy or depressed with thoughts of killing one's self. suicidal irritable irritability is the negative emotion of quick excitability to annoyance, impatience, or anger. irritability indecisiveness indecision is the emotion of being unable to choose between two or more possible courses of action. indecision a temporal qualifier is pertains to the frequency of the event of interest. temporal qualifier none of the time never refers to in none of the occasions. never some of the time some refers to in the minority of occasions some of the time most of the time most refers to in the majority of occasions most of the time all of the time always indicates that the event occurs at all times. always quality descriptor very poor quality poor quality neither good nor poor quality good quality very good quality quantity modifier An ovopub is an information content entity that contains and links to one or more resources and/or statements, including those describing its provenance, and is itself a dereferenceable resource. ovopub+ ovopub A collection ovopub is an ovopub that contains and links to one or more assertion subgraphs and/or ovopubs, as well as statements describing its provenance. It is used to share a specific set of items or restrict a search to the resources contained therein. collection ovopub An assertion ovopub is an ovopub that contains and links to an assertion subgraph with one or more statements that may be true or false, as well as statements describing its provenance. assertion ovopub none quantifier a little quantifier moderately quantifier mostly quantifier completely quantifier satisfaction qualifier very dissatisfied qualifier dissatisfied qualifier neither satisfied or dissatisfied qualifier satisfied qualifier excellent quality the date at which an information content entity was made public. date of issue an ordered list of authors. author list an ordered list is a list in which items are sequentially ordered. ordered list a middle name is a name assigned to an individual that is not the first or last name. middle name a middle initial is an abbreviated middle name. middle initial a telephone number is an identifier used to connect to a physical device capable of transfering voice or data over a network. telephone number a cellular phone number is a number to connect to a mobile device cellular phone number a fax number is a number to connect to fax device fax number IP address an IP number is an number to connect to a device on the internet. IP number an email address is an identifier to send mail to particular electronic mailbox. email address a work phone number is the number to connect to an phone at a place of work. work phone number a home phone number is the number to connect to an phone at a place of residence. home phone number status descriptor is a descriptor for the state of a process or object. status descriptor A protein expression value is a quantity obtained from a protein expression experiment. protein expression value CNV copy number variation refers to the number of deletions/duplications of a DNA region as compared to some reference state. copy number variation SNP SNV single nucleotide variation a single nucleotide variation (SNV) is a nucleotide residue that is a variant compared to some reference nucleic acid sequence. single nucleotide polymorphism metadata is data that provides information about data. metadata A diagnosis is the result of a medical investigation to identify a disorder from its signs and symptoms. diagnosis dag a directed acyclic graph or DAG is a network digram that contains directed edges in which nodes may have multiple parents, but there are no cycles. directed acyclic graph an arc is a closed segment of a differentiable curve. arc an edge is a line connecting two graph vertices. edge vertex a node or vertex is a point in a graph. node An epimer is a stereoisomer that differs in configuration at only one stereogenic center. epimer epimer association 2 a mereological quality is a quality of an entity vis-a-vis containment or parthood mereological quality empty is the quality of not containing some thing empty full is the quality of contain an entity such that there is no more space for any additional entity. full a containment quality is a quality of being able to contain another entity. containment quality A gene-disease association in which a gene mutation is known to modify the clinical presentation of the disease. gene-disease association linked with modifying mutation A gene-disease association in which a germline mutation in the gene predisposes to the development of the disease, and it is necessary but not sufficient for the manifestation of the disease. gene-disease association linked with susceptibility mutation A gene-variant disease association in which a germline mutation in the gene/protein results in the development or maintenance of the disease, and it may be passed on to offspring. gene-disease association linked with germline causal mutation A gene-variant disease association in which a somatic mutation in the gene/protein results in the development or maintenance of the disease, and it may not be passed on to offspring. gene-disease association linked with somatic causal mutation A gene-variant disease association in which a somatic mutation in the gene modifies the clinical presentation of the disease, and it may not be passed on to offspring. gene-disease association linked with somatic modifying mutation A gene-variant disease association in which a germline mutation in the gene modifies the clinical presentation of the disease, and it may be passed on to offspring. gene-disease association linked with germline modifying mutation A gene-disease association in which the fusion between two different genes (promotor and/or other coding DNA regions) is associated with the disease. fusion gene-disease association A gene-disease association in which the gene is included in a chromosomal rearrangement associated with a particular manifestation of the disease. gene-disease association linked with chromosomal rearrangement a gene-disease association that is linked with some genomic alteration gene-disease association linked with genomic alterations DisGeNET Disease specificity is a measure of disease coverage. It is calculated from the negative base 2 log of the ratio of number of diseases associated to the total number of diseases. The measure is described here: http://www.disgenet.org/web/DisGeNET/menu/dbinfo#specificity DisGeNET disease specificity The DisGeNET pleiotropy index is a measure of specificity as it pertains to classes of disease. The disease pleotropy index is computed from the ratio of the number of disease classes associated with an entity over the total number of disease classes multplied by 100. The measure is defined here: http://www.disgenet.org/web/DisGeNET/menu/dbinfo#pleiotropy DisGeNET Pleiotropy Index specialized object A week is a period of 7 consecutive days. week Specific gravity is the ratio of the density of a substance to the density of a reference substance; equivalently, it is the ratio of the mass of a substance to the mass of a reference substance for the same given volume. specific gravity information encoding speech is the expression of thoughts and feelings by sound. speech the capability to retrieve a (digitial/physical/mental) object from a location. to retrieve information translation information decoding to store is the capability to place an object into a medium in which it can be retrieved in the future. to store the capability to encode information in a different representation to encode information the capability to maintain information such that it can be retrieved in the future. to maintain information the ability to reverse an encoding operation to decode information The amount of change accumulated per unit time. rate of change regulation of information the regulation or maintenance of information information maintenance Frequency is the number of occurrences of a repeating event per unit time frequency Speed is the rate of change of an object's position. speed The rate of change of an object's position and the direction of that change velocity A slide is an visual representation meant to communicate some information. slide A statute is a formal written enactment of a legislative authority that governs a state, city or country. statute A legal document proposing or enacting a law or a group of laws. legislation A legal document is a formally executed written document that can be formally attributed to its author, records and formally expresses a legally enforceable act, process, or contractual duty, obligation, or right, and therefore evidences that act, process, or agreement. legal document A brief is a written legal document used in various legal adversarial systems that is presented to a court arguing why one party to a particular case should prevail. brief book section A bill is proposed legislation under consideration by a legislature. bill a versioned dataset is a dataset with a particular release date or release number. versioned dataset an analyte is a substance or chemical constituent of interest in an analytical procedure. analyte A protein domain is a part of a protein that maintains its structure and function independently of the rest of the protein. protein domain a protein family is a collection of proteins that share a common evolutionary origin, reflected by their related function and similarity in composition or structure. protein family a genomic sequence variant is part of a nucleic acid which is compositionally different than another reference genomic part. variant genomic sequence variant a unigene cluster is a collection of transcripts (ESTs and mRNAs) that map to a particular genomic region. cluster of transcripts unigene cluster a gene symbol is a short name assigned to a gene. gene symbol a statement of consequence is a statement concerning the result or effect of an action or condition. statement of consequence a notation is a series or system of written symbols used to represent numbers, amounts, or elements. notation a notation to describe a chemical entity chemical notation InCHI notation sequence variation notation The HGVS (human genome variation society) notation is a notation to specify a sequence variation in dna, rna, proteins, and other biomolecules. hgvs notation A protein coding sequence (CDS) is the region of DNA that is translated to form proteins. The CDS refers to those nucleotides (concatenated exons) that can be divided into codons which are actually translated into amino acids by the ribosomal translation machinery. CDS coding sequence protein coding sequence an ontology is a formal specification of entities, their attributes and relationships. ontology A biologic, also known as a biologic medical product, biological, or biopharmaceutical, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. biologic a post-translational modification is a part of a protein that was added, removed, or modified as a result of a chemical reaction after synthesis. post-translational modification evidence is the body of facts or information indicating whether a belief or proposition is true or valid. evidence oligosaccharide saccharide a carbohydrate is an organic molecule composed of two or more monosaccharides. carbohydrate 2 A terminology is a set of terms used for a specified application. terminology A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression. miRNA microRNA (miRNA) a medical intervention is a medical procedure to treat (to cure or alleviate) a health condition. medical intervention chemical exposure is a process to expose one or more individuals to a chemical substance. chemical exposure subcellular entity intersex is a biological sex characterised by birth with genitalia and/or secondary sexual characteristics of indeterminate sex, or which combine features of both sexes. intersex Density (volumetric mass density) is the quantity of mass per unit volume of a substance. density The surface area of a is a measure of the total area that the surface of the object occupies. surface area The aspect ratio of a geometric shape is the ratio of its sizes in different dimensions. aspect ratio object relational quality refers to a quality in relation to one or more objects object relational quality synthetic quality is the quality of a manufactured object that has similar properties as naturally occuring objects. synthetic quality sample quality is the quality of an object that is drawn from a larger population. sample quality replica quality is the quality of an object that is an exact copy of another object. replica quality A percentage is a number that is a ratio expressed as a fraction of 100. It is denoted using the percent sign "%". percentage A quantile is a quantity that divides the range of a probability distribution into continuous intervals with equal probabilities, or dividing the observations in a sample in the same way. quantile A percentile (or a centile) is a quantile that divides the given probability distribution, or sample, into 100 equal-sized intervals. percentile a duplicate role is a comparative role that holds when one item is an exact copy of another in a specific set. duplicate role a replicate role is a comparative role that holds when one item is a reproduction, facsimile, or a copy of another. replicate role a replicate is an object that is a facsimile, reproduction, or copy of another item. replicate replicates a collection of replicates is a collection composed of items that are a facsimile, reproduction, or copy of other items in the collection. a collection of replicates a duplicate is an object that is an exact copy of another item duplicate duplicates a collection of duplicates is a collection composed of items that are an exact copy of other items in the collection. a collection of duplicates salt a chemical salt is a molecular complex composed of an ionic assembly of cations and anions. chemical salt a strong chemical salt is a chemical salt that is composed of strong electrolytes. Strong chemical salts contain Na,K,NH4 or NO3, CIO4, CH3COO. strong chemical salt a weak chemical salt is a chemical salt composed of weak eletrolytes. weak chemical salt a peptide is an organic polymer composed of between two and fifty amino acids. peptide an oligopeptide is an organic polymer composed of fewer than 10 or 15 amino acids. oligopeptide an amino acid polymer is an organic polymer composed of two or more amino acid residues. amino acid polymer 2 an ingredient is a chemical substance that forms part of a mixture. ingredient a tensor is a n-dimensional array. tensor rank 1 tensor a vector is a rank 1 tensor that is described by n-dimension of scalars. vector rank 0 tensor a scalar is a rank 0 tensor and is an element of a field that is used to define a vector space. scalar a vector space is a set of vectors. vector space 0 rank 2 tensor a matrix is a rank 2 tensor. It is represented as a rectangular array or table of numbers, symbols, or expressions arranged in rows and columns. matrix a rank nonzero tensor is a tensor with a rank greater than zero. rank nonzero tensor A chemical-chemical association is an association between two chemical entities. chemical-chemical association 2 A disease-disease association is an association between two diseases. disease-disease association 2 A gene-gene association is an association between two genes. gene-gene association 2 A protein-protein association is an association between two proteins. protein-protein association 2 A protein-disease association is an association between a protein and a disease. protein-disease association A chemical-protein association is an association between a chemical and a protein. chemical-protein association An imaginary number is a complex number whose real part is zero e.g. 0 + bi, and is expressed as a multiple of the square root of -1. 5i is an imaginary number, and its square is -25. imaginary number a real number is a complex number whose imaginary part is zero, e.g. a + 0i. real number a complex number is an element of a number system that extends the real numbers with an imaginary unit i. Every complex number can be expressed in the form a + bi, where a and b are real numbers. complex number 1 1 the quality of existing only in the imagination. it can be used to describe concepts, ideas, or things that are the product of a cognitive process. imaginary a protein isoform is a protein that is a structural variant (different sequence of amino acids and/or post-translational modifications) of another protein, but encoded by the same gene. protein isoform a salt is a heterogeneous substance that is coposed of positively charged ions (cations) and negatively charged ions (anions) held together by electrostatic forces. salt A biological organisn is a biological entity that consists of one or more cells and is capable of genomic replication (independently or not). organism A cell is a biological entity that is contained by a plasma membrane. cell A tissue is a mereologically maximal collection of cells that together perform some function. tissue An organ is a collection of tissues joined in structural unit to serve a common function. organ A chemical entity is a material entity that pertains to chemistry. CHEBI:23367 chemical+ chemical entity atom, ion, molecule, chemical substance, A weak submolecular component is a submolecular component that weakly connects submolecular components. weak submolecular component A polypeptide is an organic polymer composed of amino acid residues, typically of less than 50 amino acids in length. polypeptide 2 A nucleic acid is an organic polymer composed of a sequence of nucleotide residues. nucleic acid 2 A ribonucleic acid is an organic polymer composed of a sequence of ribonucleotide residues. ribonucleic acid 2 A deoxyribonucleic acid is an organic polymer composed of a sequence of deoxyribonucleotide residues. deoxyribonucleic acid 2 A lipid is a water-insoluable organic molecule. lipid A chemical interaction is a biochemical process in which chemical entities interact through some set of attractive forces. biopax:Interaction chemical interaction A primary structure descriptor describes a biomolecular object in terms of a 1D or 2D topology. primary structure descriptor amino acid sequence polypeptide sequence A protein acid sequence is the character representation of the molecular structure of a protein. protein sequence A nucleic acid sequence is a symbolic representation of the sequence of nucleic acid residues in a nucleic acid. nucleic acid sequence RNA sequence A ribonucleic acid sequence is a symbolic representation of the sequence of ribonucleic acid residues in a ribonucleic acid. ribonucleic acid sequence DNA sequence A deoxyribonucleic acid sequence is a symbolic representation of the sequence of deoxyribonucleic acid residues in a deoxyribonucleic acid. deoxyribonucleic acid sequence biological data is scientific data relevant to biology. biological data A submolecular entity is a chemical entity that is a part of a molecule. submolecular entity A secondary structure descriptor describes local topological patterns in a biopolymer. secondary structure descriptor A tertiary structure descriptor describes 3D topological patterns in a biopolymer. tertiary structure descriptor A quaternary structure descriptor describes topological patterns in a multi-unit biopolymer complex. quaternary structure genetic polymorphism is the description of a difference in genetic composition at some location. genetic polymorphism genetic data is data pertaining to genetics. genetic data biological sex is the quality of a biological organism based on reproductive function or organs. biological sex A monosaccharide is an organic molecule that consists of a single polyhydroxy aldehyde or ketone group. monosaccharide A PDB chain identifier is a alphabetical label to identify a molecule in a structure provided by the Protein DataBank . PDB chain identifier A PDB record identifier is an identifier for a PDB generated record. PDB record identifier A hydrogen bond is a weak submolecular interaction formed between a hydrogen atom and a electronegative atom. hydrogen bond A cation pi interaction is an ionic interaction between the localized negative charge of π orbital electrons, located above and below the plane of an aromatic ring, and a positive charge. cation pi interaction A gene is part of a nucleic acid that contains all the necessary elements to encode a functional transcript. biopax:Gene http://purl.obolibrary.org/obo/SO_0000704 gene A biochemical reaction is a biochemical process that involves the conversion of at least one chemical participant (target) into another (product) by an enzyme (agent). biopax:BiochemicalReaction biopax:Conversion biochemical reaction A chemical element is a (effectively) homogeneous substance composed of one type of atom. chemical element A drug is a chemical substance that contains one or more active ingredients that regulate one or more biological processes. drug medicine A pharmaceutical preparation is a chemical substance that is approved for use in the medical diagnosis, cure, treatment, or prevention of disease. pharmaceutical drug A binding site is a molecular site which when occupied with particular ligands leads to structural transformations that initiatiate new moelcular processes. binding site An active site is a molecular site in which a chemical event occurs (structural transformation or conformational change). active site A haplotype is one of a set of genomic sequence variants. haplotype A protein is an organic polymer that is composed of one or more linear polymers of amino acids. CHEBI:36080 protein An atom is composed of a core of protons and/or neutrons which may be surrounded by a cloud of electrons. atom A base pair is a weak molecular interaction composed of hydrogen bonds between nucleobases. base pair A biological entity is a heterogeneous substance that contains genomic material or is the product of a biological process. chemical- biological entity A strong submolecular component is a submolecular component that strongly connects submolecular components. strong submolecular component male is a biological sex of an individual with male sexual organs. PATO:0000384 male A moleclar site is a spatial region bounded (in part or in whole) by a molecule and may be occupied by other material entities (e.g. drugs). molecular site An allosteric site is a binding site that when bound to particular ligand changes the conformational state and affects its functionality. allosteric site A biological fluid is a fluid of biological origin. biological fluid female is a biological sex of an individual with female sexual organs. female evolutionary lineage is a sequence of species, that form a line of descent, each new species the direct result of speciation from an immediate ancestral species. evolutionary lineage A cell line is a collection of genetically identifical cells. cell line A strain is a genetic variant or kind of microorganism. strain A phenotype is an observable characteristic of an individual. phenotype life status is the quality of whether something is alive or dead. life status alive is the state of a biological organism that exhibits biological functions. alive dead is the quality of an object in which there is a cessation of all biological functions. dead family history is the systematic narrative and research of past events relating to a specific family, or specific families. family history generation number is a count of the number of biological reproduction events elapsed from some starting reference point. generation number The five prime untranslated region (5' UTR) is a section of messenger RNA (mRNA) and the DNA that codes for it that starts at the +1 position (where transcription begins) and ends one nucleotide before the start codon (usually AUG) of the coding region. 5' untranslated region bioinformatic data is data genereated or used for computer-based investigations of biological phenomena. bioinformatic data A sequence alignment is the character-based alignment of sequences using some method. sequence alignment A multiple sequence alignment is a sequence alignment involving more than two sequences. multiple sequence alignment A pairwise sequence alignment is the alignment of exactly 2 sequences. pairwise sequence alignment A three prime untranslated region (3'-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. 3' untranslated region An organic submolecule is connected region of a molecule. organic submolecule An organic molecule is a molecule composed of organic atoms (at least carbon, hydrogen, and optionally oxygen, phosphorus, nitrogen, sulfur) organic molecule An open reading frame (ORF) is a part of a gene that encodes a protein but does not contain a stop codon. open reading frame 1 1 An amino acid residue is a submolecule of an amino acid that is part of a larger molecule. amino acid residue A nucleotide residue is a part of a molecule that derives from a nucleotide. nucleotide residue A poison is a drug that is harzardous or toxic to an organism when ingested at a certain quantity. poison An active ingredient is a molecular entity that exhibits biological activity. active ingredient An operon is a collection of contiguous genes transcribed as a single (polycistronic) mRNA. SO:0000178 operon A gene regulatory component is a gene component that exerts a regulatory function. gene regulatory component A gene enhancer is a short region of DNA that can be bound with proteins to enhance transcription levels of genes in a gene cluster. gene enhancer Aninactive ingredient is a molecular entity that does not exhibit biological activity. inactive ingredient to serve as a template for molecular synthesis is the capability of a chemical entity to provide the necessary information or scaffold by which another molecule may be produced. to serve as a template for molecular synthesis to serve as a template for protein synthesis is the capability of a chemical entity to provide the necessary information or scaffold by which a protein may be produced. to serve as a template for protein synthesis to serve as a template for RNA synthesis is the capability of a chemical entity to provide the necessary information or scaffold by which an RNA molecule may be produced. to serve as a template for RNA synthesis to serve as a template for DNA synthesis is the capability of a chemical entity to provide the necessary information or scaffold by which a DNA molecule may be produced. to serve as a template for DNA synthesis A deoxyribonucleic acid template is a deoxyribonucleic acid that provides the template to synthesize a complementary strand of DNA through transcription. deoxyribonucleic acid template A deoxyribonucleic acid primer is a deoxyribonucleic acid that enables the synthesis of a complement strand of DNA by binding to it and acting as a point of transcription initiation. deoxyribonucleic acid primer to serve as a primer for DNA synthesis is the capability of a short nucleic acid to bind to the 5' end of single strand of DNA template and help initiate DNA replication. to serve as a primer for DNA synthesis An RNA transcript component is a region of an RNA transcript. RNA transcript component A mature RNA is a ribonucleic acid that contains an untranslated region (UTR) and protein coding sequence and lacks introns. mature mRNA Precursor mRNA (pre-mRNA) is a single strand of messenger ribonucleic acid (mRNA) that is synthesized from a DNA template throught transcription. pre-mRNA An mRNA splice variant is an mRNA molecule that varies from another mRNA molecule of the same gene origin but having a different final sequence due to differences in its assembly from splice sites. mRNA splice variant A messenger RNA is a ribonucleic acid that contains an untranslated region (UTR) and protein coding sequence and lacks introns. messenger RNA A gene that is located on DNA. dna gene A gene that is located on RNA. rna gene An allele is one of a set of sequence variants of a gene. allele ploidy is the cellular quality relating to the amount of DNA contained in a cell. ploidy chemical transport is the directed movement of a chemical entity by some agent (e.g. transporter). biopax:Transport chemical transport active transport is the movement of a substance across a membrane against its concentration gradient (from low to high concentration) and requires chemical energy. biopax:TransportWithBiochemicalReaction active transport molecular complex formation is the process of forming a molecular complex from its constituent parts. molecular complex formation molecular complex disassociation is the process of dissambly of a molecular complex into its constitutent parts. molecular complex dissociation regulation of biochemical process is a process that changes the frequency, rate or extent of a target biochemical process. regulation of biochemical process biochemical activation is a molecular interaction that increases the catalytic rate of the target enzyme. biochemical activation biochemical inhibition is a molecular interaction that decreases the catalytic rate of the target enzyme. biochemical inhibition positive regulation process up-regulation is a process that increases the frequency, rate or extent of one or more processes in relation to a reference state. process up-regulation negative regulation process down-regulation is a process that decreases the frequency, rate or extent of one or more processes in relation to a reference state. process down-regulation medical data is data of interest to medicine. medical data disease is the outward manifestation of one or more disorders. disease transcription is the process of creating a complementary RNA copy of a sequence of DNA. transcription translation is the process of producing a polypeptide from a ribonucleic acid by a ribosome. translation Molecular modification is chemical alteration of a known and previously characterized lead compound for the purpose of enhancing its usefulness as a drug. This could mean enhancing its specificity for a particular body target site, increasing its potency, improving its rate and extent of absorption, modifying to advantage its time course in the body, reducing its toxicity, changing its physical or chemical properties (like solubility) to provide desired features. molecular modification Metabolism is the set of chemical processes that occur within a living organism in order to maintain life. metabolism Anabolism is the set of metabolic processes that take apart larger chemical entities units into smaller chemical entities. catabolism Anabolism is the set of metabolic processes that construct larger chemical entities units from smaller chemical entities. anabolism A carbohydrate residue is a part of a molecule that was derived from a monosaccharide molecule. carbohydrate residue A nucleic acid part is a component of a nucleic acid. nucleic acid part A deoxyribonucleotide residue is a part of a molecule that derives from a deoxyribonucleotide. deoxyribonucleotide residue A ribonucleotide residue is a part of a molecule that derives from a ribonucleotide. ribonucleotide residue A pharmaceutical ingredient is a part of a pharmaceutical preparation. pharmaceutical ingredient to covalently modify is to materially change a molecule by adding or removing covalent bonds between atoms. to covalently modify A chemical complex is a chemical substance composed of weakly connected molecules and ions in a known stoichiometry. chemical complex An enzyme is a protein or protein complex that realizes its disposition to covalently modify some molecule during a chemical reaction. enzyme A catalyst is a molecule that has the capability to reduce the activation energy of a reaction and hence increase the overall rate of reaction. catalyst A chemical reaction is a process that leads to the transformation of one set of chemical substances to another. chemical reaction An organic polymer is an organic molecule composed of connected set of monomeric units. organic polymer to modify conformation of is to affect the spatial arrangement of an entity. to modify conformation of to cleave is to split or sever an object along a natural line or grain. to cleave to combine is the capability to modify a set of objects in a way that the object is merged with another object to form a new object or substance. to combine to breathe is the capability to inhale and exhale air into the body during respiration. to breathe to conformationally activate is to modify the conformation of an entity in such a way that it becomes activated or functional. to conformationally activate to conformationally inhibit is to modify the conformation of an entity in such a way that it functionally is reduced or inhibited. to conformationally inhibit to oxidize is the capability to remove an electron or an increase in oxidation state of a chemical entity. to oxidize to reduce is the capability to add an electron or an decrease in oxidation state of a chemical entity. to reduce to modify the oxidation state of is to change the number of electrons of a molecule, atom or ion. to modify oxidation state of A substrate is a molecule that is consumed in the course of a biochemical reaction. substrate product to be modified is the capability to be actively interacted with in such a way that it leads to a physical reconfiguration. to be modified to be cleaved is the capability to be modified in a way that splits one part of the object from the other. to be cleaved to be covalently modified is the capability of a chemical entity to have bonds added or removed to be covalently modified to be combined is the capability to be modified in a way that the object is merged with another object to form a new object or substance. to be combined to be transported is the disposition to undergo motion. to be transported to be electronically modified is the capability of a chemical entity to have electrons added or removed. to be electronically modified to gain an electron is the capability of a chemical entity to receive an electron. to gain an electron to lose an electron is the capability of a chemical entity to lose an electron. to lose an electron to be activated is the capability to be modified in such a way that the conformational change leads to an increase in another capability. to be activated to be inhibited is the capability to be modified in such a way that the conformational change leads to an decrease in another capability. to be inhibited to be conformationally changed is the capability to be modified in such a way that the object's conformation is changed. to be conformationally changed A multi-cellular organism is an organism that consists of more than one cell. multicellular organism 2 A unicellular organism is a organism that is composed of a single cell. unicellular organism A cellular organism is an organism that contains one or more cells. cellular organism A non-cellular organism is an organism that does not contain a cell. non-cellular organism A virus is a non-cellular organism that can replicate only inside the living cells of an organism. virus A drug regulatory authority is a regulatory authority which acts to control what substances may be used to treat individuals. drug regulatory authority A specialized material entity is a material entity that is defined by having some quality, role or capability. specialized material entity A reagent is a substance that is added to a system in order to bring about a chemical reaction, or added to see if a reaction occurs. reagent A specimen is a portion of material for use in testing, examination, or study. specimen A pathogen or infectious agent is a microorganism that causes disease in its host. pathogen A host is an organism that harbors a parasite, or a mutual or commensal symbiont, typically providing nourishment and shelter. host A buffer is a dissolved chemical substance that resists change in pH upon addition of small amounts of acid or base. buffer A solvent is a substance that can dissolve other substances (solutes). solvent A solute is a substance that becomes dissolved in a solvent. solute An antigen is a molecule that can be bound by a major histocompatibility complex (MHC) and presented to a T-cell receptor. antigen A receptor molecule is a molecule that has the capability to bind to a signal and propogate a response to that signal. receptor target A centrifugation pellet is a solid substance that forms as a result of compaction by a centrifuge. centrifugation pellet A supernatent is a liquid substance that remains after centrifugation. supernatant A centrifugation substance is a substance that is the target or product of centrifugation. centrifugation substance A liquid solution component is a part of a liquid solution. liquid solution component An evaluation role is a processual role held by an entity during some evaluation. evaluation role A placebo is a medically ineffectual treatment for a medical condition intended to deceive the recipient. placebo A test role is the role of an individual that is a participant in the study and is the target of the intervention. test role A control role is the role of an individual that is part of a study, but is not subject to the intervention that is to be tested. control role A ligand is a molecule that is part of a complex by weakly interacting with another molecule. ligand A low barrier hydrogen bond is a shorter, stronger hydrogen bond that is formed between both heteroatoms. low barrier hydrogen bond A molecular activator is a molecular regulator that realizes its disposition to conformationally change a target molecule and increase its functionality. activator A molecular inhibitor is a molecular regulator that realizes its disposition to conformationally change a target molecule and decrease its functionality. inhibitor A molecular regulator is a molecule that regulates the function of another chemical entity. molecular regulator A signal transducer is a molecule that responds to and amplifies a signal in a signalling system. signal transducer A signal is an object that initiates a sequence of events. signal A mesenger is a molecule involved in either signal detection or signal propagation from receptors on the cell surface to target molecules inside the cell, in the cytoplasm or nucleus. messenger A second messenger is a molecule that relay signals from receptors on the cell surface to target molecules inside the cell, in the cytoplasm or nucleus. second messenger A submolecule is any part of a molecule. submolecule charge quality is the quality pertaining to electric charge. charge quality An intron is a region of a gene that is removed from the final protein open reading frame. intron A gene component is a component of a gene. gene component An exon is a nucleotide sequence encoded by a gene that remains present within the final mature RNA product of that gene after introns have been removed by RNA splicing. exon A gene promoter is a region of DNA that initiates transcription of a particular gene. gene promoter A start codon is the first codon of a messenger RNA (mRNA) transcript translated by a ribosome. The start codon is almost always preceded by an untranslated region 5' UTR. start codon A stop codon (or termination codon) is a nucleotide triplet within messenger RNA that signals a termination of translation. stop codon An RNA transcript is an RNA molecule that is produced from transcription of a nucleic acid template. RNA transcript A splice site is a region required for the excision of an intron and connection to another exon. splice site A molecular pocket is a site on a molecule that appears as a depression into the structure. molecular pocket An acid is a molecular entity in solution capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid). acid A base is a molecular entity dissolved in a solvent that is capable of accepting a proton (Bronsted base) or forming a covalent bond with a hydron (Lewis base) . base An isomer is a molecule that is compositionally identical to another molecule as a result of a different atomic connectivity. isomer An ion is an atom or molecule in which the total number of electrons is not equal to the total number of protons, giving it a net positive or negative electrical charge. ion An anion is an atom or molecule with a net positive electrical charge. cation An anion is an atom or molecule with a net negative electrical charge. anion A polar solvent is a solvent that exhibits a polar quality. polar solvent A non-polar solvent is a solvent that exhibits a non-polar quality. nonpolar solvent A positive charge is a charge where the value is positive. positive charge A heterogeneous substance is a chemical substance that is composed of more than one different kind of component. heterogeneous substance A homogeneous substance is a substance that is composed of a uniform type of entity. homogeneous substance A negative charge is a charge where the value is negative. negative charge An antibody (also known as immunoglobulins, abbreviated Ig) are gamma globulin proteins that are used by the immune system to identify and neutralize foreign objects. They are typically made of two large heavy chains and two small light chains. antibody An alpha helix is structural region of a protein that is characterized by 3.6 residues per turn, a translation of 1.5 angstroms along the helical axis in which backbone N-H groups form a hydrogen bond to the backbone carboxyl group of the amino acid four residues prior. alpha helix A beta strand is structural region of a protein that is characterized by a roughly planar sequence of amino acid residues forming hydrogen bonds between the N-O and the C=O of another part of the peptide and having their side chains perpendicular to the planar axis. beta strand An amino acid polymer submolecule is a submolecule of an amino acid polymer. amino acid polymer submolecule An ionic interaction is a weak submolecular interaction between a charged submolecules. ionic interaction A protein complex is a molecular complex composed of at least two polypeptide chains. protein complex 2 A single bond is a covalent bond between a pair of atoms in which one pair of electrons are shared. single bond A double bond is a covalent bond between a pair of atoms in which two pairs of electrons are shared. double bond A triple bond is a covalent bond between a pair of atoms in which three pairs of electrons are shared. triple bond An aromatic bond is an interaction between a set of atoms across which pairs of electrons are shared. aromatic bond A disulfide bond is a bond between two sulfur atoms. disulfide bond A dipole-dipole interaction is a weak submolecular interaction between strongly electronegative atoms. dipole-dipole interaction van der Waals' interaction is an a weak submolecular interaction between an instantaneous dipole and induced dipole. van der Waals interaction A base stack is a stabilizing interaction of DNA and RNA between spatially adjacent nucleotides and possibly involving London dispersion, hydrophobic and electrostatic forces. base stack A molecular complex is a chemical complex composed of at least one weakly interacting molecule. molecular complex An acid-base reaction is a chemical reaction between an acid and a base. acid-base reaction A catalyzed reaction is a chemical reaction that is facilitated by a catalyst. catalyzed reaction A redox reaction is a chemical reaction in which there is a net movement of electrons from one reactant to another. redox reaction An inorganic reaction is a chemical reaction that involves the transformation of inorganic molecules. inorganic reaction A decomposition reaction is an inorganic reaction in which molecule is fragmented into submolecules or atoms. decomposition reaction A displacement reaction is an inorganic reaction in which a elementary substance displaces and sets free a constituent atom from a molecule. displacement reaction A double displacement reaction is a displacement reaction in which two molecules swap ions, effectively displacing each other to form two new molecules. double displacement reaction A single displacement reaction where one atom is transferred out of one molecule and into another. single displacement reaction A synthesis reaction is an inorganic reaction in which two or more molecules are chemically bonded together to produce a single product. synthesis reaction An organic reaction is a chemical reaction involving at least one organic molecule. organic reaction An isomerization reaction is a chemical reaction in which a molecule is converted into its isomer. isomerization reaction An addition reaction is an organic reaction where two or more molecules combine to form a larger one. Addition reactions are limited to chemical compounds that have multiply-bonded atoms: * Molecules with carbon-carbon double bonds or triple bonds * Molecules with carbon - hetero double bonds like C=O or C=N addition reaction A polar addition reaction is an addition reaction involving polar residues. polar addition reaction A non-polar addition reaction is an addition reaction involving non-polar residues. non-polar addition reaction A free radical addition is a non-polar addition reaction involving free radicals. free radical addition A nucleophilic addition reaction is an addition reaction where a pi bond is removed by the creation of two new covalent bonds by the addition from a nucleophile. nucleophilic addition reaction An electrophilic addition reaction is a polar addition reaction where a pi bond is removed by the creation of two new covalent bonds. electrophilic addition reaction A biochemical pathway specifies a series of biochemical modifications and transformations towards achieving some biological outcome. biochemical pathway A chemical reaction pathway specifies a series of chemical reactions towards producing some chemical product. chemical reaction pathway A chemical synthesis pathway is a pathway involved in the assembly of a chemical. chemical synthesis pathway A chemical degradation pathway is a pathway involved in the disassembly of a chemical. chemical degradation pathway A 3D structure model is a representation of the spatial arrangement of one or more chemical entities. 3d structure model A sequence profile is provides the preference for a character at each position of an abstracted sequence. sequence profile A metabolic pathway is a series of biochemical reactions that begins with one or more substrates and ends with one or more products. metabolic pathway A regulatory pathway is a series of biochemical reactions that lead to the increase or decrease of activity of participating molecular components. regulatory pathway A medical history is a record of the events of a recipient of medical care. medical history A binary compound is a mereological maximum sum of two kinds of weakly connected entities. binary compound 2 A stereoisomer is an isomer in which the atomic connectivity is the same, but differs in its spatial arrangement of atoms. stereoisomer A diastereomer is a stereoisomer that is not a mirror image of its isomer. diastereomer An enantiomer is a stereoisomer that is a mirror image of its isomer. enantiomer An optical isomer is a stereoisomer that rotates the plane of polarization of a beam of plane polarized light. optical isomer A structural isomer is an isomer in which the atoms are joined together in different ways. structural isomer A ring is a submolecule with a circular topology. ring 3 An aromatic ring is a ring in which the electrons are delocalized across all atoms in the ring. aromatic ring A heterocyclic ring is a ring containing a hetero atom. heterocyclic ring A homocyclic ring is a ring where the atoms are of a single type. homocyclic ring An ionic compound is a mereological maximal sum of weakly connected paired positive and negative ions. ionic compound 1 1 An allotrope is a structural variant of a chemical element. allotrope A carbon allotrope is a chemical substance composed of carbon. carbon allotrope diamond is a carbon allotrope in which each carbon atom in diamond is covalently bonded to four other carbons in a tetrahedron. These tetrahedrons together form a 3-dimensional network of puckered six-membered rings of atoms. diamond graphite is an allotrope of carbon which is a conductor, and is the most stable form of solid carbon. graphite fullerene is a carbon allotrope which take the form of a hollow sphere, ellipsoid, or tube. fullerene aggregate of carbon nanorods is an allotrope of carbon considered to be the least compressible material known, as measured by its isothermal bulk modulus; aggregated diamond nanorods have a modulus of 491 gigapascals (GPa), while a conventional diamond has a modulus of 442 GPa. ADNRs are also 0.3% denser than regular diamond. aggregated carbon nanorods amorphous carbon is an allotrope of carbon that does not have any crystalline structure. As with all glassy materials, some short-range order can be observed, but there is no long-range pattern of atomic positions. amorphous carbon carbon nanofoam is an allotrope of carbon that consists of a low-density cluster-assembly of carbon atoms strung together in a loose three-dimensional web. Each cluster is about 6 nanometers wide and consists of about 4000 carbon atoms linked in graphite-like sheets that are given negative curvature by the inclusion of heptagons among the regular hexagonal pattern. carbon nanofoam chaoite is an allotrope of carbon that is slightly harder than graphite with a reflection colour of grey to white. chaoite glassy carbon is an allotrope of carbon which is widely used as an electrode material in electrochemistry, as well as for high temperature crucibles and as a component of some prosthetic devices. glassy carbon ionsdaleite is a hexagonal allotrope of the carbon allotrope diamond. ionsdaleite boron atom CHEBI:27560 carbon atom CHEBI:27594 hydrogen atom CHEBI:49637 helium atom CHEBI:30217 lithium atom CHEBI:30145 beryllium atom CHEBI:30501 nitrogen atom CHEBI:25555 oxygen atom CHEBI:25805 fluorine atom CHEBI:24061 neon atom CHEBI:33310 sodium atom CHEBI:26708 magnesium atom CHEBI:25107 aluminium atom CHEBI:28984 silicon atom CHEBI:27573 phosphorus atom CHEBI:28659 sulfur atom CHEBI:26833 chlorine atom CHEBI:23116 argon atom CHEBI:49475 potassium atom CHEBI:26216 calcium atom CHEBI:22984 scandium atom CHEBI:33330 titanium atom CHEBI:33341 vanadium atom CHEBI:27698 chromium atom CHEBI:28073 manganese atom CHEBI:18291 iron atom CHEBI:18248 cobalt atom CHEBI:27638 nickel atom CHEBI:28112 copper atom CHEBI:28694 zinc atom CHEBI:27363 gallium atom CHEBI:49631 germanium atom CHEBI:30441 arsenic atom CHEBI:27563 selenium atom CHEBI:27568 bromine atom CHEBI:22927 krypton atom CHEBI:49696 rubidium atom CHEBI:33322 strontium atom CHEBI:33324 yttrium atom CHEBI:33331 zirconium atom CHEBI:33342 niobium atom CHEBI:33344 molybdemum atom CHEBI:28685 technetium atom CHEBI:33353 ruthenium atom CHEBI:30682 rhodium atom CHEBI:33359 palladium atom CHEBI:33363 silver atom CHEBI:30512 cadmium atom CHEBI:22977 indium atom CHEBI:30430 tin atom CHEBI:27007 antimony atom CHEBI:30513 tellurium atom CHEBI:30452 iodine atom CHEBI:24859 xenon atom CHEBI:49957 caesium atom CHEBI:30514 barium atom CHEBI:32594 lanthanum atom CHEBI:33336 hafnium atom CHEBI:33343 tantalum atom CHEBI:33348 tungsten atom CHEBI:27998 rhenium atom CHEBI:49882 osmium atom CHEBI:30687 iridium atom CHEBI:49666 platinum atom CHEBI:33364 gold atom CHEBI:29287 mercury atom CHEBI:25195 thallium atom CHEBI:49920 lead atom CHEBI:25016 bismuth atom CHEBI:33301 polonium atom CHEBI:33313 astatine atom CHEBI:30415 radon atom CHEBI:33314 francium atom CHEBI:33323 radium atom CHEBI:33325 actinium atom CHEBI:33337 rutherfordium atom CHEBI:33346 dubnium atom CHEBI:33349 seaborgium atom CHEBI:33351 bohrium atom CHEBI:33355 hassium atom CHEBI:33357 meitnerium atom CHEBI:33361 darmstadtium atom CHEBI:33367 roentgenium atom CHEBI:33368 copernicium atom CHEBI:33517 unutrium atom ununquadium atom ununpentium atom ununhexium atom ununseptium atom ununoctium atom cerium atom CHEBI:33369 praseodymium atom CHEBI:49828 neodymium atom CHEBI:33372 promethium atom CHEBI:33373 samarium atom CHEBI:33374 europium atom CHEBI:32999 gadolinium atom CHEBI:33375 terbium atom CHEBI:33376 dysprosium atom CHEBI:33377 holmium atom CHEBI:49648 erbium atom CHEBI:33379 thulium atom CHEBI:33380 ytterbium atom CHEBI:33381 lutetium atom CHEBI:33382 thorium atom CHEBI:33385 protactinium atom CHEBI:33386 uranium atom CHEBI:27214 neptunium atom CHEBI:33387 plutonium atom CHEBI:33388 americium atom CHEBI:33389 curium atom CHEBI:33390 berkelium atom CHEBI:33391 californium atom CHEBI:33392 einsteinium atom CHEBI:33393 fermium atom CHEBI:33394 mendelevium atom CHEBI:33395 nobelium atom CHEBI:33396 lawrencium atom CHEBI:33397 A covalent bond is a strong submolecular interaction between atoms. covalent bond CHEMINF:000063 2 A biomolecular structure descriptor is structure description for organic compounds. biomolecular structure descriptor A molecular structure file is a file that contains a description of molecular structure. molecular structure file molecular structure descriptor is data that describes some aspect of the molecular structure (composition) and is about some chemical entity. molecular structure descriptor CHEMINF:000085 A chemical datum is a scientific data item which conforms to some specification, either for how it is calculated or for how it is measured, and is commonly used in the domain of chemistry to name and differentiate different numeric properties (both calculated and measured) which are about chemical entities. chemical data CHEMINF:000123 A molecule is a single chemical entity composed of fully covalently bonded atoms. molecule CHEBI:23367 mixture A chemical substance is a chemical entity composed of two or more weakly (non-covalently) interacting chemical entities. chemical substance CHEMINF:440533 A PDB file is a molecular structure file specified by the Protein DataBank (PDB). PDB file A collection of 3D molecular structure models is just that. collection of 3d molecular structure models